PMID | Title | Experiments | Integrated |
#23994476 |
Increased Mammalian Lifespan and a Segmental and Tissue-Specific Slowing of Aging after Genetic Reduction of mTOR Expression. |
0 |
False |
|
#20404021 |
Dietary amelioration of locomotor, neurotransmitter and mitochondrial aging. |
0 |
False |
|
#21471153 |
The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans. |
0 |
False |
|
#18335035 |
SirT1 regulates energy metabolism and response to caloric restriction in mice. |
0 |
False |
|
#23695394 |
A Dwarf Mouse Model With Decreased GH/IGF-1 Activity That Does Not Experience Life-Span Extension: Potential Impact of Increased Adiposity, Leptin, and Insulin With Advancing Age. |
0 |
False |
|
#11039916 |
The effect of different light regimes on adult life span in Drosophila melanogaster is partly mediated through reproductive output. |
0 |
False |
|
#23698443 |
Mitonuclear protein imbalance as a conserved longevity mechanism. |
0 |
False |
|
#23691220 |
Dietary Restriction Depends on Nutrient Composition to Extend Chronological Lifespan in Budding Yeast Saccharomyces cerevisiae. |
0 |
False |
|
#22055505 |
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog. |
0 |
False |
|
#15695762 |
Lifespan extension and elevated hsp gene expression in Drosophila caused by histone deacetylase inhibitors. |
0 |
False |
|
#18809674 |
Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster. |
0 |
False |
|
#19209226 |
Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening. |
0 |
False |
|
#18478054 |
An RGS-containing sorting nexin controls Drosophila lifespan. |
0 |
False |
|
#21111239 |
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. |
0 |
False |
|
#21826223 |
Drosophila carrying pex3 or pex16 mutations are models of Zellweger syndrome that reflect its symptoms associated with the absence of peroxisomes. |
0 |
False |
|
#18678867 |
Life span extension and neuronal cell protection by Drosophila nicotinamidase. |
0 |
False |
|
#18775584 |
Overexpression of metal-responsive transcription factor (MTF-1) in Drosophila melanogaster ameliorates life-span reductions associated with oxidative stress and metal toxicity. |
0 |
False |
|
#18083727 |
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function. |
0 |
False |
|
#18208580 |
Acquired temperature-sensitive paralysis as a biomarker of declining neuronal function in aging Drosophila. |
0 |
False |
|
#21776417 |
Loco signaling pathway in longevity. |
0 |
False |
|
#18494863 |
The farnesylated nuclear proteins KUGELKERN and LAMIN B promote aging-like phenotypes in Drosophila flies. |
0 |
False |
|
#21029723 |
dGIPC is required for the locomotive activity and longevity in Drosophila. |
0 |
False |
|
#18275960 |
Overexpression of Drosophila juvenile hormone esterase binding protein results in anti-JH effects and reduced pheromone abundance. |
0 |
False |
|
#15346199 |
Trichostatin A extends the lifespan of Drosophila melanogaster by elevating hsp22 expression. |
0 |
False |
|
#19011900 |
Adult-specific over-expression of the Drosophila genes magu and hebe increases life span and modulates late-age female fecundity. |
0 |
False |
|
#18258192 |
Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan in Drosophila. |
0 |
False |
|
#20589912 |
Life-span phenotypes of elav and Rbp9 in Drosophila suggest functional cooperation of the two ELAV-family protein genes. |
0 |
False |
|
#20018689 |
Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance. |
0 |
False |
|
#18221418 |
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype. |
0 |
False |
|
#17999718 |
Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion. |
0 |
False |
|
#19302370 |
Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans. |
0 |
False |
|
#18665908 |
14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila. |
0 |
False |
|
#16054055 |
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly. |
0 |
False |
|
#15133470 |
The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila. |
0 |
False |
|
#17159295 |
Involvement of Drosophila Sir2-like genes in the regulation of life span. |
0 |
False |
|
#23648059 |
Prolonged Lifespan with Enhanced Exploratory Behavior in Mice Overexpressing the Oxidized Nucleoside Triphosphatase hMTH1. |
0 |
False |
|
#23636330 |
Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. |
0 |
False |
|
#22405073 |
Pten positively regulates brown adipose function, energy expenditure, and longevity. |
0 |
False |
|
#23468654 |
Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans. |
0 |
False |
|
#20017609 |
Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster. |
0 |
False |
|
#20976250 |
Lifespan extension by preserving proliferative homeostasis in Drosophila. |
0 |
False |
|
#21296648 |
The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation. |
0 |
False |
|
#22982350 |
Resveratrol attenuates oxidative damage and ameliorates cognitive impairment in the brain of senescence-accelerated mice. |
0 |
False |
|
#23023872 |
Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. |
0 |
False |
|
#23105098 |
Resveratrol inhibits the proliferation of neural progenitor cells and hippocampal neurogenesis. |
0 |
False |
|
#23055713 |
Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease. |
0 |
False |
|
#23104101 |
Seven sirtuins for seven deadly diseases of aging. |
0 |
False |
|
#23293221 |
Resveratrol protects against age-associated infertility in mice. |
0 |
False |
|
#22960591 |
Effects of resveratrol on longevity, cognitive ability and aging-related histological markers in the annual fish Nothobranchius guentheri. |
0 |
False |
|
#23242337 |
[Reversal of aging and lifespan elongation : Current biomedical key publications and the implications for geriatrics.] |
0 |
False |
|
#23363784 |
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. |
0 |
False |
|
#21215371 |
The cell-non-autonomous nature of electron transport chain-mediated longevity. |
0 |
False |
|
#17516143 |
The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice. |
0 |
False |
|
#23349740 |
Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity. |
0 |
False |
|
#23300461 |
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation. |
0 |
False |
|
#23300685 |
Anti-Inflammatory Lactobacillus rhamnosus CNCM I-3690 Strain Protects against Oxidative Stress and Increases Lifespan in Caenorhabditis elegans. |
0 |
False |
|
#11021802 |
Regulation of C. elegans life-span by insulinlike signaling in the nervous system. |
0 |
False |
|
#16441844 |
Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans. |
0 |
False |
|
#23291977 |
Sesamin extends the mean lifespan of fruit flies. |
0 |
False |
|
#23291976 |
Mechanism underlying prolongevity induced by bifidobacteria in Caenorhabditis elegans. |
0 |
False |
|
#17506834 |
Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol. |
0 |
False |
|
#16784770 |
Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast. |
0 |
False |
|
#22871733 |
pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. |
0 |
False |
|
#23235143 |
Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. |
0 |
False |
|
#14583653 |
Can growth hormone (GH) accelerate aging? Evidence from GH-transgenic mice. |
0 |
False |
|
#16278235 |
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice. |
0 |
False |
|
#18729070 |
Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23. |
0 |
False |
|
#16436465 |
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. |
0 |
False |
|
#17183314 |
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis. |
0 |
False |
|
#11950998 |
Premature aging in mice deficient in DNA repair and transcription. |
0 |
False |
|
#17872905 |
Lack of fibulin-3 causes early aging and herniation, but not macular degeneration in mice. |
0 |
False |
|
#16675955 |
ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency. |
0 |
False |
|
#17143283 |
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. |
0 |
False |
|
#14690422 |
Caveolin-1 null (-/-) mice show dramatic reductions in life span. |
0 |
False |
|
#16144468 |
Oxidative stress and aging: catalase is a longevity determinant enzyme. |
0 |
False |
|
#17188333 |
Caspase-2 deficiency enhances aging-related traits in mice. |
0 |
False |
|
#16476774 |
Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice. |
0 |
False |
|
#12533509 |
Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform. |
0 |
False |
|
#17420720 |
Brca1 heterozygous mice have shortened life span and are prone to ovarian tumorigenesis with haploinsufficiency upon ionizing irradiation. |
0 |
False |
|
#17360389 |
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice. |
0 |
False |
|
#19620979 |
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. |
0 |
False |
|
#12540856 |
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. |
0 |
False |
|
#8917548 |
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. |
0 |
False |
|
#8843194 |
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. |
0 |
False |
|
#2394907 |
Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice. |
0 |
False |
|
#5723482 |
Free radical theory of aging: effect of free radical reaction inhibitors on the mortality rate of male LAF mice. |
0 |
False |
|
#16847346 |
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. |
0 |
False |
|
#17227869 |
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes. |
0 |
False |
|
#6334792 |
Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. |
0 |
False |
|
#9972869 |
Prolongation of life in an experimental model of aging in Drosophila melanogaster. |
0 |
False |
|
#23246004 |
dSir2 in the Adult Fat Body, but Not in Muscles, Regulates Life Span in a Diet-Dependent Manner. |
0 |
False |
|
#23271974 |
The GATA Transcription Factor egl-27 Delays Aging by Promoting Stress Resistance in Caenorhabditis elegans. |
0 |
False |
|
#23247094 |
Autophagy induction extends lifespan and reduces lipids content in response to frataxin silencing in C. elegans. |
1 |
False |
|
#23239738 |
A steroid receptor-microRNA switch regulates life span in response to signals from the gonad. |
0 |
False |
|
#18486188 |
Dietary lipoic acid supplementation can mimic or block the effect of dietary restriction on life span. |
0 |
False |
|
#23242215 |
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. |
3 |
False |
|
#22935001 |
Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain. |
0 |
False |
|
#15754958 |
[Effect of antidiabetic drug diabenol on parameters of biological age, life span and tumor development in NMRI and HER-2/neu mice]. |
0 |
False |
|
#23077661 |
Activation of AMPK by the Putative Dietary Restriction Mimetic Metformin Is Insufficient to Extend Lifespan in Drosophila. |
0 |
False |
|
#20304770 |
Metformin supplementation and life span in Fischer-344 rats. |
0 |
False |
|
#21164223 |
Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice. |
0 |
False |
|
#16224592 |
Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice. |
0 |
False |
|
#21386129 |
If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. |
0 |
False |
|
#20090912 |
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. |
0 |
False |
|
#18728386 |
Metformin slows down aging and extends life span of female SHR mice. |
1 |
False |
|
#16125352 |
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. |
1 |
False |
|
#12707040 |
Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice. |
0 |
False |
|
#19741171 |
Vitamin C restores healthy aging in a mouse model for Werner syndrome. |
0 |
False |
|
#15115755 |
A Werner syndrome protein homolog affects C. elegans development, growth rate, life span and sensitivity to DNA damage by acting at a DNA damage checkpoint. |
0 |
False |
|
#23075628 |
Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging. |
0 |
False |
|
#21637768 |
Polyhydroxy fullerenes (fullerols or fullerenols): beneficial effects on growth and lifespan in diverse biological models. |
0 |
False |
|
#17079053 |
A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice. |
0 |
False |
|
#15451059 |
A biologically effective fullerene (C60) derivative with superoxide dismutase mimetic properties. |
0 |
False |
|
#22498298 |
The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene. |
1 |
True |
|
#20550518 |
Longevity is not influenced by prenatal programming of body size. |
0 |
False |
|
#12725740 |
The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. |
1 |
False |
|
#21889502 |
The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis. |
0 |
False |
|
#21810936 |
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. |
4 |
False |
|
#15192154 |
Long-lived Drosophila with overexpressed dFOXO in adult fat body. |
0 |
False |
|
#12399591 |
Timing requirements for insulin/IGF-1 signaling in C. elegans. |
0 |
False |
|
#22107964 |
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice. |
0 |
False |
|
#23185716 |
Minocycline effect on life and health span of Drosophila melanogaster. |
2 |
True |
|
#17637672 |
Delayed ageing through damage protection by the Arf/p53 pathway. |
0 |
False |
|
#23173729 |
A metabolic signature for long-life in the c. Elegans mit mutants. |
0 |
False |
|
#20732954 |
Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism. |
0 |
False |
|
#23172930 |
Absence of Cardiotrophin 1 Is Associated With Decreased Age-Dependent Arterial Stiffness and Increased Longevity in Mice. |
1 |
False |
|
#23172144 |
An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. |
4 |
True |
|
#23167605 |
Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. |
6 |
False |
|
#22559237 |
Transcriptome analysis of a long-lived natural Drosophila variant: a prominent role of stress- and reproduction-genes in lifespan extension. |
0 |
False |
|
#11095759 |
Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. |
0 |
False |
|
#20607427 |
Flies selected for longevity retain a young gene expression profile. |
0 |
False |
|
#23106705 |
GENOMIC BASIS OF AGING AND LIFE-HISTORY EVOLUTION IN DROSOPHILA MELANOGASTER. |
0 |
False |
|
#22482727 |
The C. elegans microRNA mir-71 acts in neurons to promote germline-mediated longevity through regulation of DAF-16/FOXO. |
0 |
False |
|
#23097426 |
Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans. |
0 |
False |
|
#22970296 |
Metabolic rate regulates L1 longevity in C. elegans. |
0 |
False |
|
#20974969 |
DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan. |
0 |
False |
|
#5961480 |
The effect of mating status, sex and genotype on longevity in Drosophila melanogaster. |
0 |
False |
|
#23133668 |
Extension of yeast chronological lifespan by methylamine. |
0 |
False |
|
#12820979 |
Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. |
0 |
False |
|
#23121290 |
Modulation of Methuselah Expression Targeted to Drosophila Insulin-producing Cells Extends Life and Enhances Oxidative Stress Resistance. |
0 |
False |
|
#22997544 |
Overexpression of Fatty-Acid-β-Oxidation-Related Genes Extends the Lifespan of Drosophila melanogaster. |
1 |
True |
|
#16434470 |
Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. |
0 |
False |
|
#21123740 |
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. |
0 |
False |
|
#19747233 |
The growth hormone receptor gene-disrupted mouse fails to respond to an intermittent fasting diet. |
0 |
False |
|
#21876806 |
Lifespan and glucose metabolism in insulin receptor mutant mice. |
0 |
False |
|
#10875265 |
Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. |
0 |
False |
|
#8108730 |
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. |
0 |
False |
|
#17103233 |
Superoxide dismutase activities in long-lived Drosophila melanogaster females: chico1 genotypes and dietary dilution. |
0 |
False |
|
#12743125 |
Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster. |
0 |
False |
|
#20923705 |
Expression of multiple copies of mitochondrially targeted catalase or genomic Mn superoxide dismutase transgenes does not extend the life span of Drosophila melanogaster. |
0 |
False |
|
#16387864 |
Involvement of Drosophila uncoupling protein 5 in metabolism and aging. |
0 |
False |
|
#17272684 |
Regulation of Drosophila life span by olfaction and food-derived odors. |
0 |
False |
|
#11951037 |
Dietary restriction in long-lived dwarf flies. |
0 |
False |
|
#11292874 |
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. |
0 |
False |
|
#19461873 |
HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. |
0 |
False |
|
#15186745 |
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. |
3 |
False |
|
#12459580 |
Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction. |
0 |
False |
|
#19851477 |
dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster. |
0 |
False |
|
#15520384 |
Sir2 mediates longevity in the fly through a pathway related to calorie restriction. |
0 |
False |
|
#19470468 |
Long-lived Indy and calorie restriction interact to extend life span. |
0 |
False |
|
#17571923 |
No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. |
0 |
False |
|
#12626742 |
Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. |
0 |
False |
|
#11118146 |
Extended life-span conferred by cotransporter gene mutations in Drosophila. |
0 |
False |
|
#15175753 |
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. |
0 |
False |
|
#16055649 |
Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. |
0 |
False |
|
#16303568 |
Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span. |
0 |
False |
|
#19747824 |
Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain. |
0 |
False |
|
#19968629 |
Perturbation of mitochondrial complex V alters the response to dietary restriction in Drosophila. |
0 |
False |
|
#19804760 |
4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila. |
0 |
False |
|
#20195512 |
Molecular evolution and functional characterization of Drosophila insulin-like peptides. |
0 |
False |
|
#21930912 |
Increased transsulfuration mediates longevity and dietary restriction in Drosophila. |
0 |
False |
|
#22348084 |
Curcumin promotes A-beta fibrillation and reduces neurotoxicity in transgenic Drosophila. |
0 |
False |
|
#22653599 |
Expression of Pink1 with α-synuclein in the dopaminergic neurons of Drosophila leads to increases in both lifespan and healthspan. |
0 |
False |
|
#18067683 |
Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. |
0 |
False |
|
#12882325 |
Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background. |
0 |
False |
|
#18285659 |
Hyperoxia exposure induced hormesis decreases mitochondrial superoxide radical levels via Ins/IGF-1 signaling pathway in a long-lived age-1 mutant of Caenorhabditis elegans. |
0 |
False |
|
#19553937 |
A conserved ubiquitination pathway determines longevity in response to diet restriction. |
0 |
False |
|
#19883616 |
Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. |
0 |
False |
|
#17023606 |
Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. |
0 |
False |
|
#19924292 |
Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. |
0 |
False |
|
#17096674 |
Dietary deprivation extends lifespan in Caenorhabditis elegans. |
0 |
False |
|
#17081160 |
Lifespan extension in Caenorhabditis elegans by complete removal of food. |
0 |
False |
|
#19229346 |
Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans. |
0 |
False |
|
#19239417 |
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. |
0 |
False |
|
#9789046 |
The genetics of caloric restriction in Caenorhabditis elegans. |
0 |
False |
|
#19783783 |
Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans. |
0 |
False |
|
#21040400 |
Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans. |
0 |
False |
|
#16387300 |
Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons. |
0 |
False |
|
#21334311 |
The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans. |
0 |
False |
|
#22132200 |
The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans. |
0 |
False |
|
#21562563 |
N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. |
0 |
False |
|
#18662544 |
An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans. |
0 |
False |
|
#19043800 |
Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43. |
0 |
False |
|
#22216122 |
Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans. |
0 |
False |
|
#20844315 |
Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#15767565 |
JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. |
0 |
False |
|
#18832074 |
SHC-1/p52Shc targets the insulin/IGF-1 and JNK signaling pathways to modulate life span and stress response in C. elegans. |
0 |
False |
|
#17266678 |
A steroid hormone that extends the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#22359667 |
C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling. |
0 |
False |
|
#18202391 |
Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity. |
0 |
False |
|
#20041217 |
TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging. |
0 |
False |
|
#21151885 |
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. |
0 |
False |
|
#15998808 |
A systematic RNAi screen for longevity genes in C. elegans. |
0 |
False |
|
#12845331 |
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#9768365 |
Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene. |
0 |
False |
|
#19293945 |
A human protein interaction network shows conservation of aging processes between human and invertebrate species. |
0 |
False |
|
#10617200 |
Regulation of lifespan by sensory perception in Caenorhabditis elegans. |
0 |
False |
|
#16782295 |
Increased lifespan in transgenic Caenorhabditis elegans overexpressing human alpha-synuclein. |
0 |
False |
|
#15688016 |
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice. |
0 |
False |
|
#22585399 |
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. |
0 |
False |
|
#22560223 |
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. |
0 |
False |
|
#1448167 |
Production of sperm reduces nematode lifespan. |
0 |
False |
|
#12447374 |
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. |
0 |
False |
|
#8247153 |
A C. elegans mutant that lives twice as long as wild type. |
0 |
False |
|
#15905404 |
Functional interaction between beta-catenin and FOXO in oxidative stress signaling. |
0 |
False |
|
#22574120 |
C. elegans rrf-1 mutations maintain RNAi efficiency in the soma in addition to the germline. |
0 |
False |
|
#18828672 |
Caenorhabditis elegans HCF-1 functions in longevity maintenance as a DAF-16 regulator. |
0 |
False |
|
#12958363 |
Autophagy genes are essential for dauer development and life-span extension in C. elegans. |
0 |
False |
|
#8034612 |
Divergent roles of RAS1 and RAS2 in yeast longevity. |
0 |
False |
|
#8900272 |
Dwarf mice and the ageing process. |
0 |
False |
|
#22737090 |
An engineering approach to extending lifespan in C. elegans. |
0 |
False |
|
#8807293 |
Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation. |
0 |
False |
|
#16720740 |
daf-16 protects the nematode Caenorhabditis elegans during food deprivation. |
0 |
False |
|
#22265419 |
HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. |
0 |
False |
|
#9794765 |
Extended life-span and stress resistance in the Drosophila mutant methuselah. |
0 |
False |
|
#8582611 |
Regulation of gene expression is linked to life span in adult Drosophila. |
0 |
False |
|
#22848679 |
NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. |
0 |
False |
|
#17173038 |
Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models. |
0 |
False |
|
#16182251 |
The budding yeast protein Chl1p has a role in transcriptional silencing, rDNA recombination, and aging. |
0 |
False |
|
#22754872 |
Lack of Ach1 CoA-Transferase Triggers Apoptosis and Decreases Chronological Lifespan in Yeast. |
0 |
False |
|
#12736687 |
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. |
0 |
False |
|
#20947565 |
Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae. |
0 |
False |
|
#11000115 |
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. |
0 |
False |
|
#18690010 |
A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery. |
0 |
False |
|
#11292860 |
Regulation of longevity and stress resistance by Sch9 in yeast. |
0 |
False |
|
#22846641 |
Grasshopper Lazarillo, a GPI-anchored Lipocalin, increases Drosophila longevity and stress resistance, and functionally replaces its secreted homolog NLaz. |
0 |
False |
|
#22843669 |
D-chiro-Inositol and Pinitol Extend the Life * Span of Drosophila melanogaster. |
0 |
False |
|
#22844336 |
The Yang-Tonifying Herbal Medicine Cynomorium songaricum Extends Lifespan and Delays Aging in Drosophila. |
0 |
False |
|
#22829775 |
Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways. |
0 |
False |
|
#20477758 |
Trehalose extends longevity in the nematode Caenorhabditis elegans. |
0 |
False |
|
#11410594 |
Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span. |
0 |
False |
|
#15141092 |
Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging. |
0 |
False |
|
#17662940 |
Type 5 adenylyl cyclase disruption increases longevity and protects against stress. |
0 |
False |
|
#22790951 |
New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound. |
0 |
False |
|
#22783207 |
Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration. |
0 |
False |
|
#22912585 |
Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. |
0 |
False |
|
#22824366 |
Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#22810224 |
Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans. |
0 |
False |
|
#22768380 |
Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans. |
0 |
False |
|
#14668850 |
Genetics: influence of TOR kinase on lifespan in C. elegans. |
0 |
False |
|
#10580504 |
The p66shc adaptor protein controls oxidative stress response and life span in mammals. |
0 |
False |
|
#20075862 |
Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway. |
0 |
False |
|
#12383511 |
Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death. |
0 |
False |
|
#19266076 |
Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast. |
0 |
False |
|
#2999848 |
A 1100-bp sequence of mitochondrial DNA is involved in senescence process in Podospora: study of senescent and mutant cultures. |
0 |
False |
|
#22156391 |
Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression. |
0 |
False |
|
#10330149 |
Mitochondrial group II introns, cytochrome c oxidase, and senescence in Podospora anserina. |
0 |
False |
|
#22170153 |
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan. |
0 |
False |
|
#12031907 |
Effects of superoxide dismutase/catalase mimetics on life span and oxidative stress resistance in the housefly, Musca domestica. |
0 |
False |
|
#11121722 |
Prevention of flight activity prolongs the life span of the housefly, Musca domestica, and attenuates the age-associated oxidative damamge to specific mitochondrial proteins. |
0 |
False |
|
#21455602 |
Prolongevity effects of a botanical with oregano and cranberry extracts in Mexican fruit flies: examining interactions of diet restriction and age. |
0 |
False |
|
#19906819 |
Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens). |
0 |
False |
|
#19264118 |
The prolongevity effect of resveratrol depends on dietary composition and calorie intake in a tephritid fruit fly. |
0 |
False |
|
#18346215 |
Longevity-fertility trade-offs in the tephritid fruit fly, Anastrepha ludens, across dietary-restriction gradients. |
0 |
False |
|
#19716408 |
Date of eclosion modulates longevity: insights across dietary-restriction gradients and female reproduction in the mexfly Anastrepha ludens. |
0 |
False |
|
#19774093 |
Adult diet affects lifespan and reproduction of the fruit-feeding butterfly Charaxes fulvescens. |
0 |
False |
|
#20609276 |
Effect of adult chill treatments on recovery, longevity and flight ability of Queensland fruit fly, Bactrocera tryoni (Froggatt) (Diptera: Tephritidae). |
0 |
False |
|
#22094291 |
Additive and interactive effects of nutrient classes on longevity, reproduction, and diet consumption in the Queensland fruit fly (Bactrocera tryoni). |
0 |
False |
|
#21904823 |
Protein:carbohydrate ratios explain life span patterns found in Queensland fruit fly on diets varying in yeast:sugar ratios. |
0 |
False |
|
#19558564 |
Nutrients, not caloric restriction, extend lifespan in Queensland fruit flies (Bactrocera tryoni). |
0 |
False |
|
#21742024 |
Life-extending dietary restriction and ovariectomy result in similar feeding rates but different physiologic responses in grasshoppers. |
0 |
False |
|
#18761078 |
Protein accumulation underlying lifespan extension via ovariectomy in grasshoppers is consistent with the disposable soma hypothesis but is not due to dietary restriction. |
0 |
False |
|
#19129143 |
Significant effects of Pgi genotype and body reserves on lifespan in the Glanville fritillary butterfly. |
0 |
False |
|
#20072627 |
Synergistic and additive effects of epigallocatechin gallate and digitonin on Plasmodium sporozoite survival and motility. |
0 |
False |
|
#18434714 |
Genetic suppression of GH-IGF-1 activity, combined with lifelong caloric restriction, prevents age-related renal damage and prolongs the life span in rats. |
0 |
False |
|
#12668588 |
Hypotension and reduced catecholamines in neuropeptide Y transgenic rats. |
0 |
False |
|
#12692087 |
Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction. |
0 |
False |
|
#12057928 |
Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model. |
0 |
False |
|
#11718806 |
The Snell dwarf mutation Pit1(dw) can increase life span in mice. |
0 |
False |
|
#22661501 |
A persistent level of Cisd2 extends healthy lifespan and delays aging in mice. |
0 |
False |
|
#22291164 |
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. |
0 |
False |
|
#9371826 |
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). |
0 |
False |
|
#22367546 |
The sirtuin SIRT6 regulates lifespan in male mice. |
0 |
False |
|
#16195414 |
Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice. |
0 |
False |
|
#17973971 |
Influence of cardiac-specific overexpression of insulin-like growth factor 1 on lifespan and aging-associated changes in cardiac intracellular Ca2+ homeostasis, protein damage and apoptotic protein expression. |
0 |
False |
|
#6608731 |
Effects of food restriction on aging: separation of food intake and adiposity. |
0 |
False |
|
#17923673 |
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity. |
0 |
False |
|
#15153176 |
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. |
0 |
False |
|
#11331780 |
Mice lacking DNA topoisomerase IIIbeta develop to maturity but show a reduced mean lifespan. |
0 |
False |
|
#11780111 |
p53 mutant mice that display early ageing-associated phenotypes. |
0 |
False |
|
#10089885 |
Longevity, stress response, and cancer in aging telomerase-deficient mice. |
0 |
False |
|
#7493016 |
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. |
0 |
False |
|
#14679299 |
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. |
0 |
False |
|
#19776219 |
Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity. |
0 |
False |
|
#10638529 |
AlphaMUPA mice: a transgenic model for increased life span. |
0 |
False |
|
#19633237 |
Overexpression of Mn superoxide dismutase does not increase life span in mice. |
0 |
False |
|
#19487311 |
Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span. |
0 |
False |
|
#15105378 |
Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG. |
0 |
False |
|
#9060969 |
Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity. |
0 |
False |
|
#11606777 |
Methionine sulfoxide reductase (MsrA) is a regulator of antioxidant defense and lifespan in mammals. |
0 |
False |
|
#19797661 |
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. |
0 |
False |
|
#15208629 |
BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice. |
0 |
False |
|
#15289464 |
Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells. |
0 |
False |
|
#10719757 |
Ubiquitous overexpression of CuZn superoxide dismutase does not extend life span in mice. |
0 |
False |
|
#15879174 |
Extension of murine life span by overexpression of catalase targeted to mitochondria. |
0 |
False |
|
#21422498 |
RasGrf1 deficiency delays aging in mice. |
0 |
False |
|
#19717971 |
Cisd2 mediates mitochondrial integrity and life span in mammals. |
0 |
False |
|
#19451219 |
Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. |
0 |
False |
|
#22028811 |
A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice. |
0 |
False |
|
#15498882 |
Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. |
0 |
False |
|
#21079617 |
No compelling evidence that sibutramine prolongs life in rodents despite providing a dose-dependent reduction in body weight. |
0 |
False |
|
#16682650 |
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. |
0 |
False |
|
#19880816 |
Disruption of the mGsta4 gene increases life span of C57BL mice. |
0 |
False |
|
#12543978 |
Extended longevity in mice lacking the insulin receptor in adipose tissue. |
0 |
False |
|
#22461615 |
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. |
0 |
False |
|
#21109196 |
Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. |
0 |
False |
|
#22253967 |
Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice. |
0 |
False |
|
#16123266 |
Suppression of aging in mice by the hormone Klotho. |
0 |
False |
|
#12483226 |
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. |
0 |
False |
|
#12933651 |
Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. |
0 |
False |
|
#11371619 |
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. |
0 |
False |
|
#8100276 |
Premature ageing in transgenic mice expressing different growth hormone genes. |
0 |
False |
|
#20080168 |
Açai palm fruit (Euterpe oleracea Mart.) pulp improves survival of flies on a high fat diet. |
0 |
False |
|
#1712294 |
The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development. |
0 |
False |
|
#16000018 |
Calories do not explain extension of life span by dietary restriction in Drosophila. |
0 |
False |
|
#22771817 |
Fertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegans. |
0 |
False |
|
#20112046 |
Role of Drosophila alkaline ceramidase (Dacer) in Drosophila development and longevity. |
0 |
False |
|
#15331597 |
Decreased lifespan in the absence of expression of the mitochondrial small heat shock protein Hsp22 in Drosophila. |
0 |
False |
|
#17592126 |
Ceramide transfer protein function is essential for normal oxidative stress response and lifespan. |
0 |
False |
|
#17368005 |
Drosophila lacking the Cdk5 activator, p35, display defective axon guidance, age-dependent behavioral deficits and reduced lifespan. |
0 |
False |
|
#18955126 |
Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity. |
0 |
False |
|
#18216496 |
Drosophila Atg7: required for stress resistance, longevity and neuronal homeostasis, but not for metamorphosis. |
0 |
False |
|
#18056421 |
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. |
0 |
False |
|
#9363888 |
Chaperoning extended life. |
0 |
False |
|
#8987567 |
Microgravity effects on Drosophila melanogaster behavior and aging. Implications of the IML-2 experiment. |
0 |
False |
|
#21319854 |
Apple polyphenols extend the mean lifespan of Drosophila melanogaster. |
0 |
False |
|
#22197903 |
Blueberry extract prolongs lifespan of Drosophila melanogaster. |
0 |
False |
|
#14677635 |
Juvenile diet restriction and the aging and reproduction of adult Drosophila melanogaster. |
0 |
False |
|
#20367621 |
Biomarkers of aging in Drosophila. |
0 |
False |
|
#14500985 |
Demography of dietary restriction and death in Drosophila. |
0 |
False |
|
#22570630 |
Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality. |
0 |
False |
|
#22768842 |
Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. |
0 |
False |
|
#17011021 |
Comparison between the effects of aging and hyperoxia on glutathione redox state and protein mixed disulfides in Drosophila melanogaster. |
0 |
False |
|
#10506576 |
Overexpression of glutathione reductase extends survival in transgenic Drosophila melanogaster under hyperoxia but not normoxia. |
0 |
False |
|
#12456885 |
RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress. |
0 |
False |
|
#11113599 |
Targeted neuronal gene expression and longevity in Drosophila. |
0 |
False |
|
#22310715 |
Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila. |
0 |
False |
|
#12620118 |
A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes. |
0 |
False |
|
#22672579 |
Nutrient-dependent requirement for SOD1 in lifespan extension by protein restriction in Drosophila melanogaster. |
0 |
False |
|
#20655917 |
The Drosophila homolog of methionine sulfoxide reductase A extends lifespan and increases nuclear localization of FOXO. |
0 |
False |
|
#19409408 |
Overexpression of methionine-R-sulfoxide reductases has no influence on fruit fly aging. |
0 |
False |
|
#18458334 |
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila. |
0 |
False |
|
#22737247 |
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. |
0 |
False |
|
#20036725 |
Gene expression profiling implicates OXPHOS complexes in lifespan extension of flies over-expressing a small mitochondrial chaperone, Hsp22. |
0 |
False |
|
#11408621 |
Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. |
0 |
False |
|
#11867705 |
High-quality life extension by the enzyme peptide methionine sulfoxide reductase. |
0 |
False |
|
#21376794 |
Sex-dependent modulation of longevity by two Drosophila homologues of human Apolipoprotein D, GLaz and NLaz. |
0 |
False |
|
#8183891 |
Protein synthesis elongation factor EF-1 alpha expression and longevity in Drosophila melanogaster. |
0 |
False |
|
#15533947 |
DNA methyltransferase gene dDnmt2 and longevity of Drosophila. |
0 |
False |
|
#15308776 |
Multiple-stress analysis for isolation of Drosophila longevity genes. |
0 |
False |
|
#16581513 |
Loss of glial lazarillo, a homolog of apolipoprotein D, reduces lifespan and stress resistance in Drosophila. |
0 |
False |
|
#16581512 |
Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan. |
0 |
False |
|
#15708981 |
Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. |
0 |
False |
|
#11868902 |
Neural-specific overexpression of drosophila plenty of SH3s (DPOSH) extends the longevity of adult flies. |
0 |
False |
|
#12610309 |
Steroid control of longevity in Drosophila melanogaster. |
0 |
False |
|
#2508089 |
Fruit flies with additional expression of the elongation factor EF-1 alpha live longer. |
0 |
False |
|
#20422037 |
Carbon dioxide sensing modulates lifespan and physiology in Drosophila. |
0 |
False |
|
#11454765 |
High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span. |
0 |
False |
|
#20600782 |
Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster. |
0 |
False |
|
#15954861 |
Enhanced catabolism of mitochondrial superoxide/hydrogen peroxide and aging in transgenic Drosophila. |
0 |
False |
|
#20453260 |
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila. |
0 |
False |
|
#12598614 |
blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration. |
0 |
False |
|
#17435236 |
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. |
2 |
True |
|
#14602080 |
JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. |
0 |
False |
|
#15659213 |
Drosophila longevity is not affected by heterochromatin-mediated gene silencing. |
0 |
False |
|
#12882356 |
The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homologue chico. |
0 |
False |
|
#16300483 |
Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction. |
0 |
False |
|
#11292875 |
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function. |
0 |
False |
|
#17921418 |
Optimization of dietary restriction protocols in Drosophila. |
0 |
False |
|
#17266676 |
The functional costs and benefits of dietary restriction in Drosophila. |
0 |
False |
|
#19823937 |
Combined effects of suppressing live yeast and of a cold pretreatment on longevity, aging and resistance to several stresses in Drosophila melanogaster. |
0 |
False |
|
#19666103 |
Contrasted effects of suppressing live yeast from food on longevity, aging and resistance to several stresses in Drosophila melanogaster. |
0 |
False |
|
#15547319 |
D-galactose-caused life shortening in Drosophila melanogaster and Musca domestica is associated with oxidative stress. |
0 |
False |
|
#19408653 |
[Changes of the life span and certain biochemical indexes on Drosophila melanogaster by ethanol exposure]. |
0 |
False |
|
#19828196 |
Cerium caused life span shortening and oxidative stress resistance in Drosophila melanogaster. |
0 |
False |
|
#18245758 |
The effects of vitamin supplementation on Drosophila life span under normoxia and under oxidative stress. |
0 |
False |
|
#21406223 |
Nectarine promotes longevity in Drosophila melanogaster. |
0 |
False |
|
#19841272 |
Water- and nutrient-dependent effects of dietary restriction on Drosophila lifespan. |
0 |
False |
|
#9226628 |
Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster. |
0 |
False |
|
#17056793 |
Drosophila melanogaster holocarboxylase synthetase is a chromosomal protein required for normal histone biotinylation, gene transcription patterns, lifespan, and heat tolerance. |
0 |
False |
|
#17709434 |
Feeding Drosophila a biotin-deficient diet for multiple generations increases stress resistance and lifespan and alters gene expression and histone biotinylation patterns. |
0 |
False |
|
#15542350 |
Biotin deficiency decreases life span and fertility but increases stress resistance in Drosophila melanogaster. |
0 |
False |
|
#22042724 |
Balance between macronutrients affects life span and functional senescence in fruit fly Drosophila melanogaster. |
0 |
False |
|
#18268352 |
Lifespan and reproduction in Drosophila: New insights from nutritional geometry. |
0 |
False |
|
#15236760 |
Lifespan extension by dietary restriction in female Drosophila melanogaster is not caused by a reduction in vitellogenesis or ovarian activity. |
0 |
False |
|
#3113991 |
Successful selection for increased longevity in Drosophila: analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity. |
0 |
False |
|
#11250117 |
Antioxidant status and stress resistance in long- and short-lived lines of Drosophila melanogaster. |
0 |
False |
|
#15288688 |
Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster. |
0 |
False |
|
#17874997 |
Dietary restriction alters demographic but not behavioral aging in Drosophila. |
0 |
False |
|
#20333234 |
Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. |
0 |
False |
|
#21443682 |
dFOXO-independent effects of reduced insulin-like signaling in Drosophila. |
0 |
False |
|
#21518241 |
Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan. |
0 |
False |
|
#19895881 |
Food presentation modifies longevity and the beneficial action of dietary restriction in Drosophila. |
0 |
False |
|
#16256171 |
Drosophila diet restriction in practice: do flies consume fewer nutrients? |
0 |
False |
|
#17125951 |
Counting calories in Drosophila diet restriction. |
0 |
False |
|
#19798443 |
Heterochromatin protein 1 (HP1a) positively regulates euchromatic gene expression through RNA transcript association and interaction with hnRNPs in Drosophila. |
0 |
False |
|
#20096722 |
Mitochondrial electron transport chain dysfunction during development does not extend lifespan in Drosophila melanogaster. |
0 |
False |
|
#22291607 |
Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. |
0 |
False |
|
#22653297 |
Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila. |
0 |
False |
|
#17875315 |
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. |
0 |
False |
|
#22363408 |
Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila. |
0 |
False |
|
#19720829 |
JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span. |
0 |
False |
|
#19420297 |
Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions. |
0 |
False |
|
#14734639 |
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress. |
0 |
False |
|
#15491684 |
Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster. |
0 |
False |
|
#18796296 |
The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila. |
0 |
False |
|
#19428445 |
Neuronal susceptibility to GRIM in Drosophila melanogaster measures the rate of genetic changes that scale to lifespan. |
0 |
False |
|
#22227001 |
Loss of circadian clock accelerates aging in neurodegeneration-prone mutants. |
0 |
False |
|
#20157575 |
The circadian clock gene period extends healthspan in aging Drosophila melanogaster. |
0 |
False |
|
#20089120 |
Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan. |
0 |
False |
|
#20435911 |
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. |
0 |
False |
|
#15466435 |
Longevity and metabolism in Drosophila melanogaster: genetic correlations between life span and age-specific metabolic rate in populations artificially selected for long life. |
0 |
False |
|
#11430488 |
Genetic analysis of extended lifespan in Drosophila melanogaster III. On the relationship between artificially selected and wild stocks. |
0 |
False |
|
#11121683 |
Postponed aging and desiccation resistance in Drosophila melanogaster. |
0 |
False |
|
#18053668 |
Interactions between injury, stress resistance, reproduction, and aging in Drosophila melanogaster. |
0 |
False |
|
#20838645 |
A naturally occurring polymorphism at Drosophila melanogaster Lim3 Locus, a homolog of human LHX3/4, affects Lim3 transcription and fly lifespan. |
0 |
False |
|
#19840842 |
Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects. |
0 |
False |
|
#20157574 |
Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy. |
0 |
False |
|
#18221413 |
Drosophila lifespan control by dietary restriction independent of insulin-like signaling. |
0 |
False |
|
#17465980 |
Dynamics of the action of dFOXO on adult mortality in Drosophila. |
0 |
False |
|
#19385039 |
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. |
0 |
False |
|
#18434551 |
Drosophila germ-line modulation of insulin signaling and lifespan. |
0 |
False |
|
#19005568 |
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. |
0 |
False |
|
#21108726 |
Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. |
0 |
False |
|
#21415465 |
Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster. |
0 |
False |
|
#12072463 |
Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. |
0 |
False |
|
#9858546 |
FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies. |
0 |
False |
|
#15130751 |
Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span. |
0 |
False |
|
#17349761 |
Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone. |
0 |
False |
|
#20157509 |
A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila. |
0 |
False |
|
#20003237 |
Identifying sexual differentiation genes that affect Drosophila life span. |
0 |
False |
|
#15834144 |
Survival analysis of life span quantitative trait loci in Drosophila melanogaster. |
0 |
False |
|
#16702433 |
High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. |
0 |
False |
|
#11063689 |
Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster. |
0 |
False |
|
#15379853 |
Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan. |
0 |
False |
|
#15013662 |
Quantitative trait loci affecting natural variation in Drosophila longevity. |
0 |
False |
|
#20686706 |
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. |
0 |
False |
|
#10638525 |
Stress resistance and longevity in selected lines of Drosophila melanogaster. |
0 |
False |
|
#10995037 |
Oxidative stress resistance: a robust correlated response to selection in extended longevity lines of Drosophila melanogaster? |
0 |
False |
|
#16518700 |
Resistance to oxidative stress induced by paraquat correlates well with both decreased and increased lifespan in Drosophila melanogaster. |
0 |
False |
|
#16026335 |
Calorie restriction delays lipid oxidative damage in Drosophila melanogaster. |
0 |
False |
|
#15328413 |
An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster. |
0 |
False |
|
#12521602 |
Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity. |
0 |
False |
|
#1379030 |
The effects of catalase gene overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. |
0 |
False |
|
#8442664 |
Effects of Cu-Zn superoxide dismutase overexpression of life span and resistance to oxidative stress in transgenic Drosophila melanogaster. |
0 |
False |
|
#20946987 |
TGF-β and insulin signaling regulate reproductive aging via oocyte and germline quality maintenance. |
0 |
False |
|
#16099946 |
The C. elegans ortholog of mammalian Ku70, interacts with insulin-like signaling to modulate stress resistance and life span. |
0 |
False |
|
#21339330 |
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. |
0 |
False |
|
#15253933 |
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. |
0 |
False |
|
#16377915 |
Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone. |
0 |
False |
|
#19801973 |
Induction of autophagy by spermidine promotes longevity. |
0 |
False |
|
#18314552 |
Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans. |
0 |
False |
|
#8473689 |
Oxygen-dependent perturbation of life span and aging rate in the nematode. |
0 |
False |
|
#22792076 |
TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans. |
0 |
False |
|
#17673661 |
Quantitative mass spectrometry identifies insulin signaling targets in C. elegans. |
0 |
False |
|
#18358814 |
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. |
0 |
False |
|
#19049972 |
Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae. |
0 |
False |
|
#17276341 |
RLE-1, an E3 ubiquitin ligase, regulates C. elegans aging by catalyzing DAF-16 polyubiquitination. |
0 |
False |
|
#21129974 |
MicroRNAs both promote and antagonize longevity in C. elegans. |
2 |
False |
|
#18331616 |
Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. |
0 |
False |
|
#16380712 |
Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. |
0 |
False |
|
#16741121 |
Checkpoint proteins control survival of the postmitotic cells in Caenorhabditis elegans. |
0 |
False |
|
#21803287 |
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. |
0 |
False |
|
#16103914 |
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. |
0 |
False |
|
#21834846 |
The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner. |
0 |
False |
|
#22570628 |
The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity. |
0 |
False |
|
#20555324 |
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. |
0 |
False |
|
#22012258 |
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. |
0 |
False |
|
#16673436 |
Caenorhabditis elegans as a screening tool for the endothelial cell-derived putative aging-related proteins detected by proteomic analysis. |
0 |
False |
|
#17934462 |
DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans. |
0 |
False |
|
#10545213 |
Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster. |
0 |
False |
|
#17592521 |
Involvement of genes required for synaptic function in aging control in C. elegans. |
0 |
False |
|
#11063684 |
Dauer formation induced by high temperatures in Caenorhabditis elegans. |
0 |
False |
|
#10377425 |
Neurosecretory control of aging in Caenorhabditis elegans. |
0 |
False |
|
#16054097 |
C. elegans tubby regulates life span and fat storage by two independent mechanisms. |
0 |
False |
|
#16244463 |
Uncoupling of longevity and paraquat resistance in mutants of the nematode Caenorhabditis elegans. |
0 |
False |
|
#8807294 |
A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans. |
0 |
False |
|
#10638523 |
The spe-10 mutant has longer life and increased stress resistance. |
0 |
False |
|
#15068796 |
C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. |
0 |
False |
|
#12620193 |
Identification of a DAF-16 transcriptional target gene, scl-1, that regulates longevity and stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#7934213 |
Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans. |
0 |
False |
|
#8350650 |
The radiation-sensitive mutant rad-8 of Caenorhabditis elegans is hypersensitive to the effects of oxygen on aging and development. |
0 |
False |
|
#8169328 |
The effects of temperature on the longevity of a radiation-sensitive mutant rad-8 of the nematode Caenorhabditis elegans. |
0 |
False |
|
#19713489 |
Starvation protects germline stem cells and extends reproductive longevity in C. elegans. |
0 |
False |
|
#10364160 |
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. |
0 |
False |
|
#15719061 |
Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans. |
0 |
False |
|
#16373574 |
A developmental timing microRNA and its target regulate life span in C. elegans. |
0 |
False |
|
#17189267 |
Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. |
0 |
False |
|
#11274053 |
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. |
0 |
False |
|
#9716135 |
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. |
0 |
False |
|
#20369008 |
Phenotypic covariance of longevity, immunity and stress resistance in the caenorhabditis nematodes. |
0 |
False |
|
#18728385 |
The effects of p53 on whole organism longevity are mediated by autophagy. |
0 |
False |
|
#11591319 |
The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans. |
0 |
False |
|
#17895432 |
Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity. |
0 |
False |
|
#18538371 |
Repeated temperature fluctuation extends the life span of Caenorhabditis elegans in a daf-16-dependent fashion. |
0 |
False |
|
#11445592 |
Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans. |
0 |
False |
|
#8601482 |
The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#11782415 |
DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. |
0 |
False |
|
#11799246 |
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. |
0 |
False |
|
#11959102 |
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75. |
0 |
False |
|
#19467242 |
C. elegans STI-1, the homolog of Sti1/Hop, is involved in aging and stress response. |
0 |
False |
|
#12750521 |
Regulation of aging and age-related disease by DAF-16 and heat-shock factor. |
0 |
False |
|
#22360389 |
Temporal requirements of heat shock factor-1 for longevity assurance. |
0 |
False |
|
#14668486 |
Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. |
0 |
False |
|
#16917064 |
Mutations that increase the life span of C. elegans inhibit tumor growth. |
0 |
False |
|
#10819307 |
Defining wild-type life span in Caenorhabditis elegans. |
0 |
False |
|
#18056973 |
Sex-specific effects of the DAF-12 steroid receptor on aging in Caenorhabditis elegans. |
0 |
False |
|
#926867 |
Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. |
0 |
False |
|
#10360574 |
Signals from the reproductive system regulate the lifespan of C. elegans. |
0 |
False |
|
#11747825 |
daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. |
0 |
False |
|
#10747056 |
Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. |
0 |
False |
|
#19662517 |
Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans. |
0 |
False |
|
#8325483 |
Absence of strong heterosis for life span and other life history traits in Caenorhabditis elegans. |
0 |
False |
|
#10708258 |
Isolating aging mutants: a novel method yields three strains of the nematode Caenorhabditis elegans with extended life spans. |
0 |
False |
|
#6632998 |
A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results. |
0 |
False |
|
#17335870 |
The Caenorhabditis elegans nicotinamidase PNC-1 enhances survival. |
0 |
False |
|
#17521386 |
Longevity determined by developmental arrest genes in Caenorhabditis elegans. |
0 |
False |
|
#10873623 |
Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans. |
0 |
False |
|
#10335847 |
A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants. |
0 |
False |
|
#11242085 |
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. |
0 |
False |
|
#17339638 |
A demographic analysis of the fitness cost of extended longevity in Caenorhabditis elegans. |
0 |
False |
|
#16435200 |
Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype. |
0 |
False |
|
#22509016 |
Midlife gene expressions identify modulators of aging through dietary interventions. |
0 |
False |
|
#17266679 |
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. |
0 |
False |
|
#12471266 |
Rates of behavior and aging specified by mitochondrial function during development. |
0 |
False |
|
#12136014 |
Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. |
0 |
False |
|
#17411345 |
Lifespan regulation by evolutionarily conserved genes essential for viability. |
0 |
False |
|
#18836529 |
A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#19627265 |
Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1. |
0 |
False |
|
#19812672 |
Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans. |
0 |
False |
|
#22185090 |
Caenorhabditis elegans Heterochromatin protein 1 (HPL-2) links developmental plasticity, longevity and lipid metabolism. |
0 |
False |
|
#17020605 |
Activated AKT/PKB signaling in C. elegans uncouples temporally distinct outputs of DAF-2/insulin-like signaling. |
0 |
False |
|
#20178781 |
Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan. |
0 |
False |
|
#20620993 |
EAK-7 controls development and life span by regulating nuclear DAF-16/FoxO activity. |
0 |
False |
|
#18241854 |
Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity. |
0 |
False |
|
#21533078 |
PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism. |
0 |
False |
|
#22577361 |
A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans. |
0 |
False |
|
#12954481 |
Life extension via dietary restriction is independent of the Ins/IGF-1 signalling pathway in Caenorhabditis elegans. |
0 |
False |
|
#18457595 |
Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans. |
0 |
False |
|
#18083317 |
Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. |
0 |
False |
|
#20862312 |
ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. |
0 |
False |
|
#8638122 |
Determination of life-span in Caenorhabditis elegans by four clock genes. |
0 |
False |
|
#14678010 |
Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. |
0 |
False |
|
#18043747 |
DAF-2/insulin-like signaling in C. elegans modifies effects of dietary restriction and nutrient stress on aging, stress and growth. |
0 |
False |
|
#12480943 |
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. |
0 |
False |
|
#9725835 |
Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. |
0 |
False |
|
#21779524 |
High glucose diets shorten lifespan of Caenorhabditis elegans via ectopic apoptosis induction. |
0 |
False |
|
#9020081 |
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. |
0 |
False |
|
#7789761 |
Genes that regulate both development and longevity in Caenorhabditis elegans. |
0 |
False |
|
#21186286 |
A potential biochemical mechanism underlying the influence of sterol deprivation stress on Caenorhabditis elegans longevity. |
0 |
False |
|
#11487591 |
Age-specific demographic profiles of longevity mutants in Caenorhabditis elegans show segmental effects. |
0 |
False |
|
#19747231 |
Mortality shifts in Caenorhabditis elegans: remembrance of conditions past. |
0 |
False |
|
#3473482 |
Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans. |
0 |
False |
|
#2392681 |
Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging. |
0 |
False |
|
#3385139 |
Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene. |
0 |
False |
|
#11470134 |
Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans. |
0 |
False |
|
#18693219 |
The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality? |
0 |
False |
|
#16826446 |
Lifespan extension of Caenorhabditis elegans following repeated mild hormetic heat treatments. |
0 |
False |
|
#19580861 |
Multiple mild heat-shocks decrease the Gompertz component of mortality in Caenorhabditis elegans. |
0 |
False |
|
#8608934 |
A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility. |
0 |
False |
|
#10219000 |
Characterization of a life-extending mutation in age-2, a new aging gene in Caenorhabditis elegans. |
0 |
False |
|
#8700226 |
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. |
0 |
False |
|
#11511092 |
Mouse coq7/clk-1 orthologue rescued slowed rhythmic behavior and extended life span of clk-1 longevity mutant in Caenorhabditis elegans. |
0 |
False |
|
#9183440 |
Increased longevity and resistance to heat shock in Drosophila melanogaster flies exposed to hypergravity. |
0 |
False |
|
#11136229 |
A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants. |
0 |
False |
|
#10202142 |
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans. |
0 |
False |
|
#17318365 |
Hormetic effects of repeated exposures to cold at young age on longevity, aging and resistance to heat or cold shocks in Drosophila melanogaster. |
0 |
False |
|
#11909680 |
Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin. |
0 |
False |
|
#12690206 |
DAF-16 target genes that control C. elegans life-span and metabolism. |
0 |
False |
|
#17608836 |
Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. |
0 |
False |
|
#18006689 |
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants. |
0 |
False |
|
#18419309 |
Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains. |
0 |
False |
|
#21614175 |
The lin-4 Gene Controls Fat Accumulation and Longevity in Caenorhabditis elegans. |
0 |
False |
|
#21765926 |
Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms. |
0 |
False |
|
#19164523 |
The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span. |
0 |
False |
|
#18536978 |
Plant adaptogens increase lifespan and stress resistance in C. elegans. |
0 |
False |
|
#12882326 |
Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin-like signals. |
0 |
False |
|
#20528576 |
A deuterohemin peptide extends lifespan and increases stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#20828537 |
Lifespan extension in Caenorhabditis elegans by DMSO is dependent on sir-2.1 and daf-16. |
0 |
False |
|
#19597959 |
Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1. |
0 |
False |
|
#21938067 |
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. |
0 |
False |
|
#20717869 |
Procyanidins from apples (Malus pumila Mill.) extend the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#15254550 |
Sirtuin activators mimic caloric restriction and delay ageing in metazoans. |
0 |
False |
|
#16256736 |
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. |
0 |
False |
|
#16777605 |
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. |
0 |
False |
|
#16280150 |
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. |
0 |
False |
|
#16860373 |
C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO. |
0 |
False |
|
#9434744 |
Targeted gene disruption of the Caenorhabditis elegans L-isoaspartyl protein repair methyltransferase impairs survival of dauer stage nematodes. |
0 |
False |
|
#19370397 |
Nicotinamide adenine dinucleotide extends the lifespan of Caenorhabditis elegans mediated by sir-2.1 and daf-16. |
0 |
False |
|
#20209166 |
WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans. |
0 |
False |
|
#22279556 |
Caenorhabditis elegans battling starvation stress: low levels of ethanol prolong lifespan in L1 larvae. |
0 |
False |
|
#17187774 |
The L-isoaspartyl-O-methyltransferase in Caenorhabditis elegans larval longevity and autophagy. |
0 |
False |
|
#21695191 |
The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans. |
0 |
False |
|
#18988854 |
Fat metabolism links germline stem cells and longevity in C. elegans. |
0 |
False |
|
#18033297 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans. |
0 |
False |
|
#18219227 |
Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. |
0 |
False |
|
#20179756 |
Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways. |
0 |
False |
|
#20925017 |
Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans. |
0 |
False |
|
#22422488 |
L: -Theanine extends lifespan of adult Caenorhabditis elegans. |
0 |
False |
|
#21932172 |
Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species. |
0 |
False |
|
#21264793 |
The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans. |
0 |
False |
|
#17711560 |
Caenorhabditis elegans integrates food and reproductive signals in lifespan determination. |
0 |
False |
|
#19112515 |
Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans. |
0 |
False |
|
#19686215 |
A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#20550516 |
Altered signalling from germline to intestine pushes daf-2;pept-1 Caenorhabditis elegans into extreme longevity. |
0 |
False |
|
#21331044 |
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. |
0 |
False |
|
#19279398 |
Autophagy genes mediate the effect of calcineurin on life span in C. elegans. |
0 |
False |
|
#15820683 |
JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. |
0 |
False |
|
#16751106 |
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. |
0 |
False |
|
#22156377 |
Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor. |
0 |
False |
|
#21533182 |
Variable pathogenicity determines individual lifespan in Caenorhabditis elegans. |
0 |
False |
|
#12618395 |
Genetic loci modulating fitness and life span in Caenorhabditis elegans: categorical trait interval mapping in CL2a x Bergerac-BO recombinant-inbred worms. |
0 |
False |
|
#17157356 |
Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. |
0 |
False |
|
#16164425 |
Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal. |
0 |
False |
|
#16300482 |
Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2. |
0 |
False |
|
#19360094 |
Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance. |
0 |
False |
|
#21386131 |
Modulation of lipid biosynthesis contributes to stress resistance and longevity of C. elegans mutants. |
0 |
False |
|
#19764929 |
Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan. |
0 |
False |
|
#8307318 |
Longevity-determining genes in Caenorhabditis elegans: chromosomal mapping of multiple noninteractive loci. |
0 |
False |
|
#8934875 |
Defining genes that govern longevity in Caenorhabditis elegans. |
0 |
False |
|
#22303358 |
A narrow quantitative trait locus in C. elegans coordinately affects longevity, thermotolerance, and resistance to paraquat. |
0 |
False |
|
#17187771 |
Multiple sensory G proteins in the olfactory, gustatory and nociceptive neurons modulate longevity in Caenorhabditis elegans. |
0 |
False |
|
#17476212 |
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. |
0 |
False |
|
#17538612 |
Two neurons mediate diet-restriction-induced longevity in C. elegans. |
0 |
False |
|
#19489741 |
Endogenous cGMP regulates adult longevity via the insulin signaling pathway in Caenorhabditis elegans. |
0 |
False |
|
#19793063 |
Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway. |
0 |
False |
|
#17900900 |
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. |
0 |
False |
|
#16626391 |
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. |
0 |
False |
|
#15574588 |
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. |
0 |
False |
|
#15837805 |
Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression. |
0 |
False |
|
#16626392 |
The nuclear hormone receptor DAF-12 has opposing effects on Caenorhabditis elegans lifespan and regulates genes repressed in multiple long-lived worms. |
0 |
False |
|
#19469880 |
Lifespan extension by suppression of autophagy genes in Caenorhabditis elegans. |
0 |
False |
|
#17204841 |
Autophagy regulates ageing in C. elegans. |
0 |
False |
|
#21906946 |
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans. |
0 |
False |
|
#17912023 |
Autophagy is required for dietary restriction-mediated life span extension in C. elegans. |
0 |
False |
|
#18282106 |
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. |
0 |
False |
|
#20590843 |
Redox regulation, gene expression and longevity. |
0 |
False |
|
#22103665 |
Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan. |
0 |
False |
|
#9504918 |
An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. |
0 |
False |
|
#20952811 |
Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans. |
0 |
False |
|
#9353126 |
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. |
0 |
False |
|
#18772467 |
Protein-repair and hormone-signaling pathways specify dauer and adult longevity and dauer development in Caenorhabditis elegans. |
0 |
False |
|
#16164423 |
LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans. |
0 |
False |
|
#21695230 |
Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. |
0 |
False |
|
#11740945 |
A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. |
0 |
False |
|
#17900898 |
The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. |
0 |
False |
|
#18692520 |
Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved? |
0 |
False |
|
#18782349 |
The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans. |
0 |
False |
|
#18024103 |
Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin. |
0 |
False |
|
#21855561 |
Curcumin-mediated lifespan extension in Caenorhabditis elegans. |
0 |
False |
|
#17096597 |
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. |
0 |
False |
|
#21503726 |
Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans. |
0 |
False |
|
#19923212 |
The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. |
0 |
False |
|
#22452899 |
Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans. |
0 |
False |
|
#14996832 |
Lack of peroxisomal catalase causes a progeric phenotype in Caenorhabditis elegans. |
0 |
False |
|
#21858156 |
Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans. |
0 |
False |
|
#19085685 |
Epigallocatechin gallate from green tea (Camellia sinensis) increases lifespan and stress resistance in Caenorhabditis elegans. |
0 |
False |
|
#19061950 |
Significant longevity-extending effects of EGCG on Caenorhabditis elegans under stress. |
0 |
False |
|
#22013497 |
Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans. |
0 |
False |
|
#20700440 |
RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. |
0 |
False |
|
#21884719 |
Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway. |
0 |
False |
|
#17914900 |
Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans. |
0 |
False |
|
#20332814 |
Genes required for the functions of olfactory AWA neuron regulate the longevity of Caenorhabditis elegans in an insulin/IGF signaling-dependent fashion. |
0 |
False |
|
#21055415 |
Regulation of longevity by genes required for the functions of AIY interneuron in nematode Caenorhabditis elegans. |
0 |
False |
|
#21713031 |
The homeobox protein CEH-23 mediates prolonged longevity in response to impaired mitochondrial electron transport chain in C. elegans. |
0 |
False |
|
#11381260 |
Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling. |
0 |
False |
|
#20824162 |
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling. |
0 |
False |
|
#19749979 |
A transcription elongation factor that links signals from the reproductive system to lifespan extension in Caenorhabditis elegans. |
0 |
False |
|
#21423649 |
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans. |
0 |
False |
|
#18423931 |
14-3-3 regulates life span by both DAF-16-dependent and -independent mechanisms in Caenorhabditis elegans. |
0 |
False |
|
#21909281 |
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. |
0 |
False |
|
#17360327 |
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. |
0 |
False |
|
#16530049 |
SMK-1, an essential regulator of DAF-16-mediated longevity. |
0 |
False |
|
#16563875 |
Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase. |
0 |
False |
|
#21749634 |
The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity. |
0 |
False |
|
#22505847 |
A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity. |
0 |
False |
|
#16530050 |
Germ-cell loss extends C. elegans life span through regulation of DAF-16 by kri-1 and lipophilic-hormone signaling. |
0 |
False |
|
#19506556 |
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. |
0 |
False |
|
#20346072 |
Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans. |
0 |
False |
|
#11709184 |
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans. |
0 |
False |
|
#11778046 |
Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q. |
0 |
False |
|
#19416129 |
p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress. |
0 |
False |
|
#20172019 |
A role for p53 in mitochondrial stress response control of longevity in C. elegans. |
0 |
False |
|
#16293572 |
Reduction of Caenorhabditis elegans frataxin increases sensitivity to oxidative stress, reduces lifespan, and causes lethality in a mitochondrial complex II mutant. |
0 |
False |
|
#15771615 |
Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans. |
0 |
False |
|
#22253756 |
Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans. |
0 |
False |
|
#12470895 |
Adaptive responses to oxidative damage in three mutants of Caenorhabditis elegans (age-1, mev-1 and daf-16) that affect life span. |
0 |
False |
|
#18073424 |
A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans. |
0 |
False |
|
#20382831 |
Decreased energy metabolism extends life span in Caenorhabditis elegans without reducing oxidative damage. |
0 |
False |
|
#18406553 |
Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans. |
0 |
False |
|
#19197346 |
Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. |
0 |
False |
|
#21931751 |
DAF-16 and Δ9 desaturase genes promote cold tolerance in long-lived Caenorhabditis elegans age-1 mutants. |
0 |
False |
|
#19164565 |
A network biology approach to aging in yeast. |
0 |
False |
|
#20799725 |
Compartmentalization and regulation of mitochondrial function by methionine sulfoxide reductases in yeast. |
0 |
False |
|
#18500447 |
Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast. |
0 |
False |
|
#17110466 |
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. |
0 |
False |
|
#19059240 |
Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast. |
0 |
False |
|
#16806052 |
MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. |
0 |
False |
|
#17174052 |
Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. |
0 |
False |
|
#16436509 |
Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging. |
0 |
False |
|
#22445853 |
Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging. |
0 |
False |
|
#18162582 |
Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. |
0 |
False |
|
#21707788 |
Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. |
0 |
False |
|
#16023114 |
Yeast HAT1 and HAT2 deletions have different life-span and transcriptome phenotypes. |
0 |
False |
|
#16527275 |
Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast. |
0 |
False |
|
#16199065 |
Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae. |
0 |
False |
|
#17492370 |
Mutations in the Atp1p and Atp3p subunits of yeast ATP synthase differentially affect respiration and fermentation in Saccharomyces cerevisiae. |
0 |
False |
|
#21906795 |
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. |
0 |
False |
|
#20729566 |
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. |
0 |
False |
|
#15489200 |
A novel assay for replicative lifespan in Saccharomyces cerevisiae. |
0 |
False |
|
#20093034 |
Ganodermasides A and B, two novel anti-aging ergosterols from spores of a medicinal mushroom Ganoderma lucidum on yeast via UTH1 gene. |
0 |
False |
|
#21597195 |
Anti-aging effects of phloridzin, an apple polyphenol, on yeast via the SOD and Sir2 genes. |
0 |
False |
|
#20550517 |
Metabolomics-based systematic prediction of yeast lifespan and its application for semi-rational screening of ageing-related mutants. |
0 |
False |
|
#22484922 |
Anti-aging effects of hesperidin on Saccharomyces cerevisiae via inhibition of reactive oxygen species and UTH1 gene expression. |
0 |
False |
|
#21371425 |
GABA metabolism pathway genes, UGA1 and GAD1, regulate replicative lifespan in Saccharomyces cerevisiae. |
0 |
False |
|
#21902802 |
Sir2 deletion prevents lifespan extension in 32 long-lived mutants. |
0 |
False |
|
#20832724 |
Elevated histone expression promotes life span extension. |
0 |
False |
|
#15126388 |
Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism. |
0 |
False |
|
#21700873 |
Gametogenesis eliminates age-induced cellular damage and resets life span in yeast. |
0 |
False |
|
#19570907 |
Budding yeast SSD1-V regulates transcript levels of many longevity genes and extends chronological life span in purified quiescent cells. |
0 |
False |
|
#9620775 |
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons. |
0 |
False |
|
#15621721 |
Ascorbate restores lifespan of superoxide-dismutase deficient yeast. |
0 |
False |
|
#12020810 |
Effect of superoxide dismutase deficiency on the life span of the yeast Saccharomyces cerevisiae. An oxygen-independent role of Cu,Zn-superoxide dismutase. |
0 |
False |
|
#10222047 |
Mitochondrial superoxide decreases yeast survival in stationary phase. |
0 |
False |
|
#9199172 |
Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast. |
0 |
False |
|
#8647826 |
Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo. |
0 |
False |
|
#12640455 |
Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan. |
0 |
False |
|
#10662670 |
Two paralogs involved in transcriptional silencing that antagonistically control yeast life span. |
0 |
False |
|
#11389927 |
The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. |
0 |
False |
|
#11742528 |
Profiles of random change during aging contain hidden information about longevity and the aging process. |
0 |
False |
|
#11861900 |
SGS1 is a multicopy suppressor of srs2: functional overlap between DNA helicases. |
0 |
False |
|
#9789734 |
Epigenetic stratification: the role of individual change in the biological aging process. |
0 |
False |
|
#19557187 |
Telomere recombination accelerates cellular aging in Saccharomyces cerevisiae. |
0 |
False |
|
#10230397 |
Elimination of replication block protein Fob1 extends the life span of yeast mother cells. |
0 |
False |
|
#9275199 |
Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae. |
0 |
False |
|
#2644196 |
Evidence for the involvement of a cytoplasmic factor in the aging of the yeast Saccharomyces cerevisiae. |
0 |
False |
|
#21482672 |
Mediator influences telomeric silencing and cellular life span. |
0 |
False |
|
#12242224 |
A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae. |
0 |
False |
|
#7806576 |
Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span. |
0 |
False |
|
#10207108 |
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. |
0 |
False |
|
#1938877 |
Telomere length constancy during aging of Saccharomyces cerevisiae. |
0 |
False |
|
#11884393 |
Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels. |
0 |
False |
|
#9150138 |
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. |
0 |
False |
|
#10430902 |
Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae. |
0 |
False |
|
#22675632 |
Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial Chaperonin Hsp60. |
0 |
False |
|
#19303850 |
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. |
0 |
False |
|
#11290710 |
The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. |
0 |
False |
|
#7859289 |
Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. |
0 |
False |
|
#12562756 |
Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing. |
0 |
False |
|
#21248481 |
Cell size and growth rate are major determinants of replicative lifespan. |
0 |
False |
|
#17172436 |
Mpt5p, a stress tolerance- and lifespan-promoting PUF protein in Saccharomyces cerevisiae, acts upstream of the cell wall integrity pathway. |
0 |
False |
|
#9428525 |
Extrachromosomal rDNA circles--a cause of aging in yeast. |
0 |
False |
|
#9271578 |
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. |
0 |
False |
|
#11756539 |
hpr1Delta affects ribosomal DNA recombination and cell life span in Saccharomyces cerevisiae. |
0 |
False |
|
#2698814 |
Replication control and cellular life span. |
0 |
False |
|
#10224252 |
Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae. |
0 |
False |
|
#12024027 |
Mutations in DNA replication genes reduce yeast life span. |
0 |
False |
|
#10521401 |
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. |
0 |
False |
|
#10921902 |
Sip2p and its partner snf1p kinase affect aging in S. cerevisiae. |
0 |
False |
|
#9851878 |
Role of RAS2 in recovery from chronic stress: effect on yeast life span. |
0 |
False |
|
#9851879 |
Heat stress-induced life span extension in yeast. |
0 |
False |
|
#8195187 |
Cloning and characterization of LAG1, a longevity-assurance gene in yeast. |
0 |
False |
|
#8760941 |
LAG2, a gene that determines yeast longevity. |
0 |
False |
|
#11805047 |
Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. |
0 |
False |
|
#19305133 |
A molecular mechanism of chronological aging in yeast. |
0 |
False |
|
#18423200 |
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. |
0 |
False |
|
#21191185 |
Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. |
0 |
False |
|
#16741098 |
Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". |
0 |
False |
|
#14729974 |
Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity. |
0 |
False |
|
#15547318 |
The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity. |
0 |
False |
|
#12586694 |
SOD2 functions downstream of Sch9 to extend longevity in yeast. |
0 |
False |
|
#17482543 |
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. |
0 |
False |
|
#15020466 |
Rtg2 protein links metabolism and genome stability in yeast longevity. |
0 |
False |
|
#18628831 |
Genomic instability is associated with natural life span variation in Saccharomyces cerevisiae. |
0 |
False |
|
#18930829 |
The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease. |
0 |
False |
|
#10620009 |
Bloom's syndrome gene suppresses premature ageing caused by Sgs1 deficiency in yeast. |
0 |
False |
|
#18195102 |
Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. |
0 |
False |
|
#19467248 |
Inactivation of the 20S proteasome maturase, Ump1p, leads to the instability of mtDNA in Saccharomyces cerevisiae. |
0 |
False |
|
#20157595 |
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. |
0 |
False |
|
#21641548 |
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling. |
0 |
False |
|
#17200108 |
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension. |
0 |
False |
|
#18381895 |
The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast. |
0 |
False |
|
#12855292 |
The Ras and Sch9 pathways regulate stress resistance and longevity. |
0 |
False |
|
#17710147 |
DNA replication stress is a determinant of chronological lifespan in budding yeast. |
0 |
False |
|
#14741356 |
Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae. |
0 |
False |
|
#20622262 |
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. |
0 |
False |
|
#18340043 |
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. |
0 |
False |
|
#22303396 |
Loss of mitochondrial membrane potential triggers the retrograde response extending yeast replicative lifespan. |
0 |
False |
|
#11024000 |
An intervention resembling caloric restriction prolongs life span and retards aging in yeast. |
0 |
False |
|
#12213553 |
Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast. |
0 |
False |
|
#10512855 |
Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. |
0 |
False |
|
#17544056 |
Low auxotrophy-complementing amino acid concentrations reduce yeast chronological life span. |
0 |
False |
|
#22615903 |
Ammonium is toxic for aging yeast cells, inducing death and shortening of the chronological lifespan. |
0 |
False |
|
#21901113 |
Natural polymorphism in BUL2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast. |
0 |
False |
|
#19458476 |
Autophagy is required for extension of yeast chronological life span by rapamycin. |
0 |
False |
|
#20421943 |
A microarray-based genetic screen for yeast chronological aging factors. |
0 |
False |
|
#19302372 |
Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae. |
0 |
False |
|
#21918615 |
Identification of longevity genes with systems biology approaches. |
0 |
False |
|
#15722108 |
Genes determining yeast replicative life span in a long-lived genetic background. |
0 |
False |
|
#20657825 |
Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation. |
0 |
False |
|
#18469137 |
Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span. |
0 |
False |
|
#19424415 |
Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. |
0 |
False |
|
#19805817 |
Deleting the 14-3-3 protein Bmh1 extends life span in Saccharomyces cerevisiae by increasing stress response. |
0 |
False |
|
#18225956 |
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. |
0 |
False |
|
#16418483 |
Extension of chronological life span in yeast by decreased TOR pathway signaling. |
0 |
False |
|
#22216232 |
A network-based approach on elucidating the multi-faceted nature of chronological aging in S. cerevisiae. |
0 |
False |
|
#19030232 |
Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity. |
0 |
False |
|
#21447998 |
A genomic analysis of chronological longevity factors in budding yeast. |
0 |
False |
|
#20713692 |
Yin and Yang of histone H2B roles in silencing and longevity: a tale of two arginines. |
0 |
False |
|
#16336970 |
Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence. |
0 |
False |
|
#20707985 |
Assessment of chronological lifespan dependent molecular damages in yeast lacking mitochondrial antioxidant genes. |
0 |
False |
|
#21076178 |
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence. |
0 |
False |
|
#20696905 |
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity. |
0 |
False |
|
#17460215 |
Effects of deleting mitochondrial antioxidant genes on life span. |
0 |
False |
|
#16782871 |
Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span. |
0 |
False |
|
#17403371 |
Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. |
0 |
False |
|
#18704665 |
Increased aerobic metabolism is essential for the beneficial effects of caloric restriction on yeast life span. |
0 |
False |
|
#20640543 |
Mitochondria-mediated hormetic response in life span extension of calorie-restricted Saccharomyces cerevisiae. |
0 |
False |
|
#16311627 |
Increased life span due to calorie restriction in respiratory-deficient yeast. |
0 |
False |
|
#15383542 |
Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae. |
0 |
False |
|
#21584246 |
Identification of potential calorie restriction-mimicking yeast mutants with increased mitochondrial respiratory chain and nitric oxide levels. |
0 |
False |
|
#17711561 |
Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. |
0 |
False |
|
#18513215 |
Caffeine extends yeast lifespan by targeting TORC1. |
0 |
False |
|
#22319457 |
Down-regulating sphingolipid synthesis increases yeast lifespan. |
0 |
False |
|
#16286010 |
Sir2 blocks extreme life-span extension. |
0 |
False |
|
#15328540 |
Sir2-independent life span extension by calorie restriction in yeast. |
0 |
False |
|
#21949725 |
Composition and acidification of the culture medium influences chronological aging similarly in vineyard and laboratory yeast. |
0 |
False |
|
#22438832 |
The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex. |
0 |
False |
|
#12124627 |
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. |
0 |
False |
|
#17129213 |
Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. |
0 |
False |
|
#16051752 |
HST2 mediates SIR2-independent life-span extension by calorie restriction. |
0 |
False |
|
#12939617 |
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. |
0 |
False |
|
#21931558 |
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. |
0 |
False |
|
#12297502 |
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. |
0 |
False |
|
#12391171 |
High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction. |
0 |
False |
|
#12788479 |
Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells. |
0 |
False |
|
#11744041 |
Loss of prohibitins, though it shortens the replicative life span of yeast cells undergoing division, does not shorten the chronological life span of G0-arrested cells. |
0 |
False |
|
#12882345 |
The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. |
0 |
False |
|
#22622083 |
Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion. |
0 |
False |
|
#9259555 |
The prohibitin family of mitochondrial proteins regulate replicative lifespan. |
0 |
False |
|
#15130665 |
Expression of the human ferritin light chain in a frataxin mutant yeast affects ageing and cell death. |
0 |
False |
|
#18059160 |
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. |
0 |
False |
|
#17617737 |
Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila. |
0 |
False |
|
#17392428 |
Regulation of Caenorhabditis elegans lifespan by a proteasomal E3 ligase complex. |
0 |
False |
|
#11462771 |
Antioxidant and antiaging activity of N-acetylserotonin and melatonin in the in vivo models. |
0 |
False |
|
#18241326 |
Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. |
0 |
False |
|
#23066506 |
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. |
0 |
False |
|
#16293764 |
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. |
0 |
False |
|
#None |
A gain-of-function screen identifies wdb and lkb1 as lifespan-extending genes in Drosophila. |
0 |
False |
|
#22366109 |
Misexpression screen delineates novel genes controlling Drosophila lifespan. |
0 |
False |
|
#23028355 |
C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress. |
2 |
False |
|
#22970337 |
Apple can act as anti-aging on yeast cells. |
0 |
False |
|
#23144747 |
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks. |
3 |
True |
|