Denigma

PaDnm1:ble

Species: Podospora anserine (Taxid: 5145)
Factor:
Manipulation: Loss-of-Function, Mutation
Effect:

Dnm1 disruption in wild-type extends mean and maximum lifespan by 377 and 329% and its disruption in long-lived grisea mutants prolongs mean and maximum lifespan by 1009 and over 1090% (survival was not followed to the end) [17173038].

Mean: +377
Maximum: +329

References:
  • 17173038: Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.


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