RAGE | — | — | Human |
CDKN2B | — | — | Human |
C4B | complement component 4B (Chido blood group) | Genetic variations in C4B are not associated with longevity in Italian [10219002]. | Human |
C3 | complement component 3 | Genetic variations in C3 are not associated with longevity in Italian [10219002]. | Human |
CFB | complement factor B | Genetic variations in CFB are not associated with longevity in Italian [10219002]. | Human |
C4A | complement component 4A (Rodgers blood group) | Genetic variations in C4A are not associated with longevity in Italian [10219002]. | Human |
F2 | Coagulation factor II (thrombin) | — | Human |
MT-RNR2 | — | An single nucleotide polymorphism in MT-RNR2 is associated with longevity [18759861]. | Human |
nhr-62 | Nuclear Hormone Receptor family | NHR-62 is required for metabolic and physiologic responses associated with DR-induced longevity. *nhr-62* mediates the longevity response of *eat-2* mutants and blunts the longevity by bacterial food dilution [Heestand, et al. 2012].
Mutation in *nhr-62* suppresses the lifespan extension of eat-2(ad465) animals (p<0.001) [Heestand et al. 2013].
Wild-type (N2) worms with extrachromosomal array dhEx627 (carrying a wild-type nhr-62) exhibit a significant increase in lifespan compared to wild-type (p<0.001) [Heestand et al. 2013]. | Nematode |
PDE10A | phosphodiesterase 10A | SNPs near PDE10A were associated to longevity [22773346]. | Human |
QKI | quaking homolog, KH domain RNA binding (mouse) | SNPs close to SQKI were associated with longevity [22773346]. | Human |
XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | XRCC5 was found to be associated with longevity [22406557; 16518718]. | Human |
XDH | xanthine dehydrogenase | XDH was found to be associated with longevity [22406557; 22279548]. | Human |
NTHL1 | nth endonuclease III-like 1 (E. coli) | NTHL1 was found to be associated with longevity [22406557]. | Human |
FOXO4 | forkhead box O4 | FOXO4 was found to be associated with longevity [21388494]. | Human |
NTLH1 | nescient helix loop helix 1 | NTLH1 was found to be associated with longevity [22406557]. | Human |
POLB | polymerase (DNA directed), beta | POLB was found to be associated with longevity [22406557]. | Human |
RAD23B | RAD23 homolog B (S. cerevisiae) | RAD23B was found to be associated with longevity [22406557]. | Human |
RAD52 | RAD52 homolog (S. cerevisiae) | RAD52 was found to be associated with longevity [22406557]. | Human |
IGF2R | insulin-like growth factor 2 receptor | IGF2R was found to be associated with longevity [22406557]. | Human |
GHSR | growth hormone secretagogue receptor | GHSR was found to be associated with longevity [22406557]. | Human |
GHRHR | growth hormone releasing hormone receptor | GHRHR was found to be associated with longevity [22406557]. GHRHR was not found to be associated with longevity [19489743]. | Human |
GSR | glutathione reductase | GSR was found to be associated with longevity [22406557]. | Human |
ICAM1 | intercellular adhesion molecule 1 | ICAM1 was found to be associated with longevity [22174011]. | Human |
RIMBP2 | RIMS binding protein 2 | RIMBP2 was found to be associated with longevity [22174011]. | Human |