197 | Figure 2 | Vacuolar acidity is reduced in ageing cells and regulates mitochondrial function and lifespan. | ✘ | S288c | VMA1(OE) | — | — | — | — | 39.0 | 39.0 | 80.0 | 56 |
356 | Figure 2. Dependence of Lifespan Extension on Overexpression in Specific Tissues | ✘ | w1118 | +/UAS-dS6KKQ | — | — | — | — | 23.0 | — | 34.0 | 115 |
221 | Figure 3. Increased life span of cardiotrophin 1 (CT-1)–null mice. | ✔ | C57BL6 | WT | — | — | — | — | — | 28.0 | — | 18 |
218 | Supplementary Figure 3. Phenotypes of VPH2 overexpression mimic those observed with VMA1 overexpression. | ✘ | S288c | VPH2(OE) | — | — | — | — | 32.0 | 32.5 | 67.0 | 52 |
307 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 26.0 | — | 31.0 | 29 |
309 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc1 | — | — | — | — | 29.0 | — | 40.0 | 136 |
308 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dTsc1 | — | — | — | — | 25.0 | — | 34.0 | 109 |
222 | Figure 3. Increased life span of cardiotrophin 1 (CT-1)–null mice. | ✘ | C57BL6 | CT-1(null) | — | — | — | — | — | 33.0 | — | 24 |
217 | Supplementary Figure 3. Phenotypes of VPH2 overexpression mimic those observed with VMA1 overexpression. | ✔ | S288c | WT | — | — | — | — | 26.0 | 26.0 | 50.0 | 53 |
313 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 26.0 | — | 31.0 | 92 |
312 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc2 | — | — | — | — | 29.0 | — | 37.0 | 112 |
311 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/dTsc2 | — | — | — | — | 25.0 | — | 34.0 | 118 |
315 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTORFRB | — | — | — | — | 30.0 | — | 40.0 | 126 |
317 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dS6KKQ | — | — | — | — | 23.0 | — | 34.0 | 115 |
316 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 26.0 | — | 31.0 | 92 |
314 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dTORFRB | — | — | — | — | 22.0 | — | 31.0 | 98 |
310 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 26.0 | — | 31.0 | 92 |
216 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✘ | S288c | VMA1(OE) | Dietary Restriction | — | — | — | 40.0 | 40.0 | 64.0 | 38 |
577 | Table 1 Lifespan analyses frh-1 dsRNA constructs - summary statistics | ✘ | — | WT | RNA Interference | frh-1 IV(RNAi) | — | — | 20.9 | — | 37.0 | 149 |
321 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dS6kSTDETE | — | — | — | — | 16.0 | — | 24.0 | 75 |
323 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dTsc2 | — | — | — | — | 56.0 | — | 74.0 | 126 |
322 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 58.0 | — | 78.0 | 133 |
320 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | +/UAS-dS6kSDETE | — | — | — | — | 24.0 | — | 31.0 | 40 |
319 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✔ | w1118 | +/da-GAL4 | — | — | — | — | 26.0 | — | 31.0 | 92 |
318 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dS6kKQ | — | — | — | — | 30.0 | — | 40.0 | 122 |