354 | Figure 2. Dependence of Lifespan Extension on Overexpression in Specific Tissues | ✘ | w1118 | DJ634-GAL4/UAS-dTORFRB | — | — | — | — | 31.0 | — | 37.0 | 107 |
521 | Figure 3. Loss of mir-14 Is Associated with Semilethality, Reduced Lifespan, Stress Sensitivity, and Increased Levels of the Caspase Drice | ✔ | — | wild-type | — | — | 20.0 | — | 31.0 | — | 42.0 | — |
334 | Figure 2. Dependence of Lifespan Extension on Overexpression in Specific Tissues | ✔ | w1118 | +/gmr-GAL4 | — | — | — | — | 31.0 | — | 42.0 | 102 |
88 | Figure 2: Overexpression of CG6783 or CG13890 throughout the whole body extends lifespan, which is associated with diet restriction. | ✔ | white1118 | Act-GS-Gal4>UAS-CG6783 | — | RU- | — | — | 31.0 | — | 65.0 | — |
137 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✔ | — | sir2;fob1 | — | — | 30.0 | — | 30.8 | 34.0 | 46.0 | 20 |
164 | Supplemental Figure 3: Growth curves and lifespan curves of respiratory dead or deficient strains | ✘ | — | idh2 | — | — | 30.0 | — | 30.7 | 31.0 | 60.0 | 595 |
186 | Figure 5: Hac1-independent resistance to tunicamycin in afg3∆ and rpl20bΔ cells | ✘ | — | afg3;hac1 | — | — | 30.0 | — | 30.7 | 32.0 | 50.0 | 40 |
175 | Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves | ✘ | — | afg3 | — | — | 30.0 | — | 30.7 | 31.0 | 43.0 | — |
348 | Figure 2. Dependence of Lifespan Extension on Overexpression in Specific Tissues | ✘ | w1118 | DJ634-GAL4/UAS-dTsc2 | — | — | — | — | 30.6 | — | 40.0 | 120 |
176 | Supplemental Figure 4: Unsuppressed growth of afg3∆, yta12∆, and mrpl32∆ and corresponding lifespan curves | ✘ | — | afg3;rho0 | — | — | 30.0 | — | 30.3 | 32.0 | 59.0 | — |
148 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | afg3rpl20b | — | — | 30.0 | — | 30.3 | 32.0 | 52.0 | 40 |
365 | Figure 3. Lifespan Extension by dTsc2 Overexpression Is Dependent on the Concentration of Yeast Extract in the Diet | ✔ | w1118 | +/da-GAL4 | — | 1% yeast extract | 29.0 | — | 30.0 | — | — | 182 |
362 | Figure 3. Lifespan Extension by dTsc2 Overexpression Is Dependent on the Concentration of Yeast Extract in the Diet | ✘ | w1118 | da-GAL4/UAS-dTsc2 | — | 0.1% yeast extract | 29.0 | — | 30.0 | — | — | 164 |
318 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dS6kKQ | — | — | — | — | 30.0 | — | 40.0 | 122 |
315 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTORFRB | — | — | — | — | 30.0 | — | 40.0 | 126 |
156 | Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses | ✘ | — | msn2;msn4 | — | — | 30.0 | — | 29.3 | 30.0 | 57.0 | 623 |
158 | Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses | ✘ | — | hac1 | — | — | 30.0 | — | 29.1 | 29.0 | 57.0 | 543 |
136 | Figure 6: Deletion of AFG3 reduces cytoplasmic translation and extends life span by a Sir2-independent, Gcn4-dependent mechanism | ✘ | — | sir2;fob1;afg3 | — | — | 30.0 | — | 29.1 | 30.0 | 45.0 | 40 |
154 | Supplemental Figure 2: Replicative lifespan curves of control strains sensitive to the tested stresses | ✘ | — | cta1 | — | — | 30.0 | — | 29.0 | 27.0 | 54.0 | 45 |
213 | Figure 4 | Calorie restriction extends lifespan by regulating vacuolar acidity. | ✔ | S288c | WT | — | — | — | — | 29.0 | 29.0 | 50.0 | 38 |
519 | Figure 3. Loss of mir-14 Is Associated with Semilethality, Reduced Lifespan, Stress Sensitivity, and Increased Levels of the Caspase Drice | ✔ | — | wild-type | — | — | 20.0 | — | 29.0 | — | 42.0 | — |
523 | Fig. 3. Animal survival and growth | ✔ | Wistar | — | Mutation | — | — | — | 29.0 | 22.0 | 38.0 | 6 |
503 | Figure 5. miR-239 and miR-71 Function through the IGF-1/Insulin-like and the DNA Damage Checkpoint Pathways | ✘ | — | wild-type | RNA Interference | daf-2(RNAi) | 20.0 | — | 29.0 | — | 34.0 | — |
312 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc2 | — | — | — | — | 29.0 | — | 37.0 | 112 |
309 | Figure 1. Regulation of Lifespan by Modulating Genes in the TOR Signaling Pathway | ✘ | w1118 | da-GAL4/UAS-dTsc1 | — | — | — | — | 29.0 | — | 40.0 | 136 |