Symbol: IDP3 Name: Isocitrate Dehydrogenase, NADP-specific 3 Entrez gene ID: 855723 Ensembl gene ID: YNL009W Species: Yeast (Taxid: 4932) Functional description: Idp3p; Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids [Source:SGD;Acc:S000004954] [Ensembl] Observation: Deletion of IDP3 results in a replicative lifespan increase by 15% in the alpha strain and decrease by 20% in the a strain [18340043; 19030232]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Note: Different effects on a and alpha strains? Edit \ Update (Admin) | Delete |
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