Symbol: cchl-1 Name: Cytochrome C Heme-Lyase Entrez gene ID: 174713 Ensembl gene ID: T06D8.6 Species: Worm (Taxid: 6239) Functional description: Holocytochrome c synthase/heme-lyase; Links covalently the heme group to the apoprotein of cytochrome c (By similarity). [UniProt] Observation: cchl-1 RNAi extends mean and maximum lifespan by 55% and 57%, respectively. Lifespan extension by RNAi of cchl-1 is not suppressed by daf-16 [12447374]. cchl-1 RNAi animals have lower ATP content and oxygen consumption [12447374]. Interventions: Assays: Organismal Lifespan Mean: +55 Maximum: +57 Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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