Symbol: AGC1 Name: Aspartate-Glutamate Carrier Entrez gene ID: 856132 Ensembl gene ID: YPR021C Species: Yeast (Taxid: 4932) Functional description: Agc1p; Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis [Source:SGD;Acc:S000006225] [Ensembl] Observation: Deletion of AGC1 increases replicative lifespan by 30% in the alpha strain [18340043] and increases mean chronological lifespan by 7 - 28% [21447998]. Assays: Mean: +7-30 Classification: Aging Relevance Analysis/Source: Homologs Note: It also decreased mean chronological lifespan by 29% in one experiment. Edit \ Update (Admin) | Delete |
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