Symbol: vit-5 Name: VITellogenin structural genes (yolk protein genes) 5 Entrez gene ID: 180630 Ensembl gene ID: C04F6.1 Species: Worm (Taxid: 6239) Functional description: function in embryongensis and in the lipoprotein formation and oxidation pathways during germ line development; Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Potential). [UniProt] Observation: RNA interference against vit-5 extends mean lifespan by 10-22%. vit-5 is differentially transcribed in daf-16 and daf-2 RNAi animals [12845331]. RNAi knockdown of vit-5 starting at hatching or only during the adulthood significantly extends lifespan of wild-type, but does not alter, or even shortens the lifespan of eat-2 mutants [22810224]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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