Symbol: Sirt2 Entrez gene ID: 42414 Ensembl gene ID: FBgn0038788 Species: Fly (Taxid: 7227) Functional description: NAD(+)-dependent histone deacetylase that silences gene expression; NAD-dependent protein deacetylase (By similarity). May be involved in the regulation of life span. [UniProt] Observation: Decreased expression of Sirt2 by RNA interference causes lethality during development. Silencing in neurons shortened mean lifespan by 20% [17159295]. Interventions: Assays: Organismal Lifespan Mean: -20 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Orthologs Inparanoids Edit \ Update (Admin) | Delete |
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