Symbol: BRE5 Name: BREfeldin A sensitivity 5 Entrez gene ID: 855787 Ensembl gene ID: YNR051C Species: Yeast (Taxid: 4932) Functional description: Bre5p; Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A [Source:SGD;Acc:S000005334] [Ensembl] Observation: Deletion of BRE5 increases mean replicative lifespan by 30% [16293764] and mean chronological lifespan in diploid cells [21447998] Interventions: Assays: Replicative Lifespan Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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