Symbol: npp-2 Name: Nuclear Pore complex Protein Entrez gene ID: 172611 Ensembl gene ID: T01G9.4 Species: Worm (Taxid: 6239) Functional description: Protein NPP-2; Nuclear Pore complex Protein family member (npp-2) [Source:RefSeq peptide;Acc:NP_492256] [Ensembl]; npp-2 encodes a protein with low similarity to rat nucleoporin Nup75 that affects embryonic viability and has a variety of other defects in RNAi screens including: nuclear morphology, growth, fertility, locomotion, and egg laying; enriched in oocytes. [WormBase] Observation: RNA interference decreased median lifespan by 11% in wild type animals, 38% in a daf-2 background and 22% in daf-2/daf-16 double mutants. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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