Symbol: nhx-2 Name: Na/H eXchanger Entrez gene ID: 174242 Ensembl gene ID: B0495.4 Species: Worm (Taxid: 6239) Functional description: Protein NHX-2; Na/H eXchanger family member (nhx-2) [Source:RefSeq peptide;Acc:NP_495614] [Ensembl]; nhx-2 encodes a sodium/proton exchanger; NHX-2 promotes normal peptide transporter function and recovery from intracellular acid load via catalysis of the electroneutral exchange of extracellular sodium for an intracellular proton; NHX-2 activity is required for normally high growth rates, and for propagation or maintenance of the germline; NHX-2 is expressed in the apical membranes of intestinal cells. [WormBase] Observation: Gene inactivation by RNA interference led to a loss of fat stores in the intestine and a 40% increase in lifespan. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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