Symbol: g Name: garnet Entrez gene ID: 44819 Ensembl gene ID: FBgn0001087 Species: Fly (Taxid: 7227) Functional description: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). May be a coat protein involved in the formation of specialized structures like pigment granules. [UniProt] Observation: Loss-of-function mutation in g reduces mean lifespan by 11 - 42% and maximum lifespan by 7 - 30% [17435236]. Interventions: Assays: Organismal Lifespan Mean: -11 to -42 Maximum: -7 to -30 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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