Symbol: erm-1 Name: Ezrin/Radixin/Moesin Entrez gene ID: 172174 Ensembl gene ID: C01G8.5 Species: Worm (Taxid: 6239) Functional description: Protein ERM-1; Ezrin/Radixin/Moesin family member (erm-1) [Source:RefSeq peptide;Acc:NP_491559] [Ensembl]; The erm-1 gene encodes an ortholog of the ERM family of cytoskeletal linkers with approximately equal similarity to ezrin, radixin and moesin. It has a somewhat more distant homology to human merlin/schwannomin (NF2), which when mutated leads to neurofibromatosis, type 2 (OMIM:101000). [WormBase] Observation: RNA interference in adulthood resulted in a 15% mean lifespan extension. Assays: Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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