Symbol: Lnk Entrez gene ID: 43130 Ensembl gene ID: FBgn0028717 Species: Fly (Taxid: 7227) Observation: Loss of Lnk function results in increased median (14% in females and 17.5 in males) and maximum lifespan, reduced female fecundity and improves survival under conditions of oxidative stress and starvation. Heterozygousity does not result in any significant differences in lifespan in either males or females. Moreover, lifespan extension in one of the female homozygous mutant is fully rescued by the introduction of a Lnk genomic rescue construct [20333234]. Interventions: Assays: Organismal Lifespan Median: -14 to -17.5 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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