Symbol: elo-5 Name: fatty acid ELOngation Entrez gene ID: 177320 Ensembl gene ID: F41H10.7 Species: Worm (Taxid: 6239) Functional description: Protein ELO-5; fatty acid ELOngation family member (elo-5) [Source:RefSeq peptide;Acc:NP_500793] [Ensembl]; The elo-5 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-5 is required for normally rapid growth and for normal fatty acid composition. In mass RNAi assays, elo-5(RNAi) animals grow abnormally slowly, and in individual assays, they display visibly altered fatty acid composition and multiple growth defects. [WormBase] Observation: RNA interference decreased median lifespan by 45% in wild type animals and 29% in daf-2 mutants. Assays: Classification: Aging Relevance Analysis/Source: Homologs Orthologs Edit \ Update (Admin) | Delete |
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