Symbol: Ef1alpha48D Name: Elongation factor 1alpha48D Alias: EF-1; Elongation factor 148D Entrez gene ID: 36271 Ensembl gene ID: FBgn0000556 Species: Fly (Taxid: 7227) Functional description: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity). [UniProt] Observation: Overexpression of Ef1alpha48D (transformed with a P-element vector and under control of hsp70 regulatory sequences) results in lifespan extension by 18-41%. The decrease in protein synthesis that accompanies aging is preceded by a decrease in EF-1 alpha protein and mRNA [2508089]. Interventions: Assays: Organismal Lifespan Mean: +18 to +41 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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