Symbol: eat-6 Name: EATing: abnormal pharyngeal pumping Entrez gene ID: 179796 Ensembl gene ID: B0365.3 Species: Worm (Taxid: 6239) Functional description: Protein EAT-6; EATing: abnormal pharyngeal pumping family member (eat-6) [Source:RefSeq peptide;Acc:NP_506269] [Ensembl]; eat-6 encodes an ortholog of the alpha subunit of a sodium/potassium ATPase, which in turn affects Na+,K(+)-ATPase activity of membranes by affecting the level of the phosphorylated intermediate of the Na+,K(+)-ATPase; EAT-6 affects relaxation of the pharyngeal muscles, fertility (and thus affects feeding); EAT-6 also affects body length, life span, and ASE, ASI and ASJ axonal outgrowth. [WormBase] Observation: Mutations in eat-6 extend lifespan by 15-40%. Lifespan extension is proposed to be similiar to DR [9789046]. eat-1 mutants have defects in haryngeal feeding behavior [8462849]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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