Symbol: ESA1 Alias: KAT5; TAS1 Entrez gene ID: 854418 Ensembl gene ID: YOR244W Species: Yeast (Taxid: 4932) Functional description: Esa1p; Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression and transcriptional silencing at the rDNA locus [Source:SGD;Acc:S000005770] [Ensembl] Observation: esa1-531 mutant has an even shorter chronological lifespan than PKA1 deletion mutant in both 2% glucose (ad libitum) and water (extreme DR) at 30 degree Celsius, a semipermissive temperature. At the permissive temperature (25 degree Celsius) there is little difference [19303850]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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