Symbol: CIT2 Name: CITrate synthase 2 Entrez gene ID: 850361 Ensembl gene ID: YCR005C Species: Yeast (Taxid: 4932) Functional description: Cit2p; Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors [Source:SGD;Acc:S000000598] [Ensembl] Observation: Deletion or overexpression of CIT2 has no effect on replicative lifespan. CIT2 is not required for the strain specific lifespan extension in petite cells [10224252], although it is transcribed up to 30-fold higher in petite cells relative to grande cells [1986232]. Interventions: Assays: Replicative Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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