Symbol: HPR1 Name: HyPerRecombination 1 Alias: TRF1 Entrez gene ID: 851716 Ensembl gene ID: YDR138W Species: Yeast (Taxid: 4932) Functional description: Hpr1p; Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p [Source:SGD;Acc:S000002545] [Ensembl] Observation: Deletion of HPR1 decreases replicative lifespan [11756539] Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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