Symbol: VPS21 Name: Vacuolar Protein Sorting 21 Alias: VPS12; VPT12; YPT21; YPT51 Entrez gene ID: 854256 Ensembl gene ID: YOR089C Species: Yeast (Taxid: 4932) Functional description: Vps21p; Rab family GTPase required for endocytic transport and for sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog [Source:SGD;Acc:S000005615] [Ensembl] Observation: Lack of VPS21 reduces lifespan under starvation conditions to a level similiar to that of wild-type cells incubated in synthetic complete medium and therefore blocked the lifespan-extending effect of DR [20657825]. Interventions: Assays: Chronological Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
Comment on This Data Unit