Symbol: T08A11.2 Name: Nuclear Hormone Receptor family Alias: hypothetical protein;WBGENE00011605 Entrez gene ID: 175549 Ensembl gene ID: T08A11.2 Species: Worm (Taxid: 6239) Functional description: Protein T08A11.2; T08A11.2 encodes the C. elegans ortholog of splicing factor 3b subunit 1, also known as SAP155; by homology, the product of T08A11.2 is predicted to be a component of the U2 snRNP that is required for pre-mRNA splicing; large-scale RNAi assays indicate that T08A11.2 activity is essential for a number of processes including embryonic development, normal adult lifespan, vulval morphogenesis, locomotion, and transgene expression and localization. [WormBase] Observation: T08A11.2 RNAi in the adulthood extends the lifespan [New longevity regulators]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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