Symbol: lam-2 Name: LAMinin related. See also lmb- Alias: LAMinin related. See also lmb- family member (lam-2);WBGENE00016913 Entrez gene ID: 180980 Ensembl gene ID: C54D1.5 Species: Worm (Taxid: 6239) Functional description: LAMinin related. See also lmb-; Protein LAM-2; Laminin-like protein lam-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18823] [Ensembl]; lam-2 encodes a laminin gamma subunit; lam-2 activity is required for embryonic development and for regulation of muscle arm extension; loss of lam-2 function via large-scale RNAi screens results in embryonic, larval, and adult lethality, sterility, body morphology defects, and abnormal locomotion. [WormBase] Observation: lam-2 RNAi in the adulthood extends the lifespan [New longevity regulators]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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