Symbol: IMD2 Name: IMP Dehydrogenase 2 Alias: PUR5 Entrez gene ID: 856626 Ensembl gene ID: YHR216W Species: Yeast (Taxid: 4932) Functional description: Imd2p; Inosine monophosphate dehydrogenase, catalyzes the rate-limiting step in GTP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitatio [Source:SGD;Acc:S000001259] [Ensembl] Observation: Deletion of IMD2 does non-significantly decrease mean replicative lifespan by 1% and non-significantly increased maximum replicative lifespan by 21% [20550517]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Note: Is the maximumm lifespan extension really not significant? Edit \ Update (Admin) | Delete |
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