Symbol: FCY1 Name: FluoroCYtosine resistance 1 Entrez gene ID: 856175 Ensembl gene ID: YPR062W Species: Yeast (Taxid: 4932) Functional description: Fcy1p; Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU) [Source:SGD;Acc:S000006266] [Ensembl] Observation: Deletion of FCY1 does non-significantly decrease mean and maximum replicative lifespan by 4% and 8%, respectively [20550517]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Note: Non-significantly decrease. Edit \ Update (Admin) | Delete |
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