Symbol: HOM6 Name: HOMoserine requiring 6 Entrez gene ID: 853604 Ensembl gene ID: YJR139C Species: Yeast (Taxid: 4932) Functional description: Hom6p; Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions [Source:SGD;Acc:S000003900] [Ensembl] Observation: Deletion of HOM6 extends mean chronological lifespan by 75 - 256% (75, 159, 202, 256) in diploid cells [21447998]. Assays: Mean: +75-256 Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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