Symbol: HFM1 Name: Helicase Family Member 1 Alias: MER3 Entrez gene ID: 852641 Ensembl gene ID: YGL251C Species: Yeast (Taxid: 4932) Functional description: Hfm1p; Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity [Source:SGD;Acc:S000003220] [Ensembl] Observation: Deletion of HFM1 increases mean chronological lifespan by 19 - 139% (19, 30, 45, 139) in diploid cells [21447998]. Assays: Mean: +19-139 Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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