Symbol: ARO7 Name: AROmatic amino acid requiring 7 Alias: HGS1;OSM2;,TYR7 Entrez gene ID: 856173 Ensembl gene ID: YPR060C Species: Yeast (Taxid: 4932) Functional description: Aro7p; Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis [Source:SGD;Acc:S000006264] [Ensembl] Observation: Under starvation/extreme DR deletion of ARO7 increases mean chronological lifespan and confers higher resistance to heat-shock, but made cell more sensitive to acetic acid and leads to growth defects. In W303-1A background ARO7 deletion causes an even more severe growth defect and mutants are short-lived [20657825]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Note: Got information from http://www.ncbi.nlm.nih.gov/pubmed/21447998 Edit \ Update (Admin) | Delete |
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