Symbol: ACB1 Name: Acyl-CoA-Binding 1 Entrez gene ID: 852925 Ensembl gene ID: YGR037C Species: Yeast (Taxid: 4932) Functional description: Acb1p; Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes; subject to starvation-induced, Grh1p-mediated unconventional secretion [Source:SGD;Acc:S000003269] [Ensembl] Observation: ACB1 deletion extends chronological lifespan under starvation/extreme DR. Similar heat-shock resistance and resistance to a very hight concentration of acetic acid (but not resistance to oxidative stress) was enhanced by the deletion of ACB1. Deletion of ACB1 in W303-1A and DBY746 genetic backgrounds on synthetic complete media causes severe growth defects and sightly shorter lifespan and also heat-sensitivity [20657825]. Interventions: Assays: Chronological Lifespan Classification: Aging Relevance Analysis/Source: Homologs Note: Strain and diet specific effects? Edit \ Update (Admin) | Delete |
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