Symbol: TIF4631 Name: Translation Initiation Factor 4631 Entrez gene ID: 853071 Ensembl gene ID: YGR162W Species: Yeast (Taxid: 4932) Functional description: Tif4631p; Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit [Source:SGD;Acc:S000003394] [Ensembl] Observation: Deletion of TIF4631 increases replicative lifespan by 20% in the alpha and a strains [18340043]. TIF4631 increases replicative lifespan by 10-20% in the alpha and a strains [19030232]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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