Symbol: NMT1 Name: N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction Entrez gene ID: 850892 Species: Yeast (Taxid: 4932) Functional description: Nmt1p; N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction [Source:SGD;Acc:S000004185] [Ensembl] Observation: nmt1-451D allele shortens mean and maximum replicative lifespan by 47 and 44% at 24 degree Celsius (permessive temperature). Mutants have decreased resistance to acute and gradual nutrient deprivation, even at the permissive temperature [10921902]. A NMT null mutant is lethal. Interventions: Assays: Replicative Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Note: Is NMT1 null mutant meant instead of NMT? Edit \ Update (Admin) | Delete |
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