| Encouraging Initiative | 1 | 2 | Wuttke; Coernette | A merit earning system build on top of the Achievements, that gives Researchers, Developers and Artists as well as other people the recognition and respect for their contribution and work need to be established. Such a system that awards merit for go... |
| Lobbying | 1 | 4 | Stambler; Khaltourina; Coernette; AgeVivo | Lobbying is the act of **attempting to influence decisions** made by officials in the government, most often legislators or members of the regular agencies. For effective lobbying it is crucial to first ``set goals and objectives``. Actions for the n... |
| Information Theory | 2 | 3 | Stambler; Wuttke; Blokh | Information theory is a field of applied mathematics, engineering and computer science that measures information.
It originates from the finding of the fundamental limits on signal processing operations, such as compressing data, and on reliable s... |
| Health Extension Media Responses And Outreach | 1 | 2 | Xu; Pellissier | ``Analyse`` and ``systemize`` **Health/Longevity Media Responses**. We need to keep track of the information that is broadcasted to the public and guarantee that it is positively interpreted and understood. Create a **portal** that Links in all the d... |
| Graph Visualization | 3 | 7 | Stambler; Kulaga; Wuttke; Nishry; Mind; Atraylen; Horusavatar | **Data on Aging** need to be **visualized** with an ``interactive`` and ``intuitive interface`` that enables ``collaborative reverse-engineering`` of the Aging process. It shall be a popular and interactive way of to convey a basic understanding of t... |
| Gerontology | 2 | 0 | | The ``Gerontology Ontology`` (the Ontology for Aging and Longevity, ``GERO``) is a mid-level ontology representing aging-related phenomena from the molecular and cellular levels to the social and demographic level. It aims to support gerontological ... |
| Circadian Clock Controls Ageing | 2 | 3 | Magalhaes; Wuttke; Wood |
:Abstract: Dietary restriction without malnutrition delays ageing and extends lifespan, but the molecular mechanism is still unknown. Ageing gene expression changes originate from development and growth cessation, are modulated by diet, and manip... |
| in situ Regeneration | 1 | 2 | Wuttke; Zamani |
:Abstract: As we are young everything regenerates perfectly. In fact, our body harbors the plan to reconstruct itself from scratch which is localized in the nucleus of each of our body cells. However, as we grow up our regenerative capacities decre... |
| Circadian Rhythm | 2 | 4 | Kapahi; Magalhaes; Wuttke; Katewa | Most animals have rest/activity/rhythms that are powered by an endogenous timing mechanism, the circadian system. With aging the rhythm becomes weaker [23223368].
Middle aged flies exhibit reduced activity level in comparison with young controls. ... |
| Denigma | 5 | 9 | Fuellen; Magalhaes; Debonneuil; Kulaga; Wuttke; Adams; Borisoglebsky; Fortney; Hall | Denigma is the digital Enigma destined to decipher biological phenomena. All information of an organism is encoded in its genome and can be decrypted via the combined effort of humans and machines. For this, Denigma was build for.
Specifically, Deni... |
| Pentose Phosphate Pathway | 2 | 3 | Magalhaes; Wuttke; Tang | The pentose phosphate pathway chiefly generates reduction equivalents in the form of NADPH:
3 G6P + 6 NADPH+ + 3 H2O = 6 NADPH + 6 H+ + 3 CO2 + 2 F6P + GAP
6 equivalents of NADPH is quite a lot for just three sugars. NADPH might scavenge ROS.
... |
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