There was a small survival advantage for centenarian and octo/nonagenarian subjects who were heterozygous for PON1 192 R allele. Detailed OR information is as follows: 1.3 (1-1.5)
Ethnicity:Irish,
Italian Age of cases: Italian 100.8 years, Irish 89.8 years Shorter lived allele: Q
Statistics - Number of cases/controls: 308 vs 579 Italian, 296 vs 296 Irish (initial)
- Odds ratio: 1.3 - p-value:
0.007
- Significant: Yes
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