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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs1799990 — — 1.0 150 vs 165 — Polish Centenarian — — Candidate Region/Gene 23406923
rs2273773 SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs3740051  SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs3758391 SIRT1 — 1.0 223 vs 277 — Chinese Average age 93 — — Candidate Region/Gene 23450480
rs4746720 SIRT1 2.10 0.0001 223 vs 277 — Chinese Average age 93 CC, TT CT Candidate Region/Gene 23450480
rs12778366 SIRT1 0.69 0.025 1390 — Dutch 36 to 79 — — Candidate Region/Gene 23505545
MNS16A TERT 0.75 0.019 200 vs 539 — Italian 88+ MNS16A*L — Candidate Region/Gene 23562826
rs1799983 NOS3 — 0.703 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs10277237 — — 0.805 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs2297518 NOS2 — 0.066 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs10459953 — — 0.522 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs2682826 NOS1 — 0.589 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs1879417 — — 0.018 321 vs 442 — Italian 89-107 — — Candidate Region/Gene 23572278
rs2701858, rs9486902 — 3.23 0.0001 1088 — Danish 92+ — — Candidate Region/Gene 23607278
rs1799752 ACE 1.16 0.001 1803 vs 10484 — Multiethnic Centenarian — D Meta-Analysis 23623925
rs1799752 ACE 1.25 0.032 1803 vs 10484 — Multiethnic Centenarian — DD Meta-Analysis 23623925
rs4673 — 1.48 0.022 — — Russian — C T Candidate Region/Gene 23755540
rs1853432 JUN — 0.52 213 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
rs17356414 JUN — 0.082 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1815274 JUN — 0.18 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
rs2999131 — — 0.31 208 vs 391 — Japanese 95+ — — Candidate Region/Gene 23770741
rs1776180 EXO1 — 0.16 206 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
rs10811661 — — 0.13 213 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
rs2511837 CBL — 0.14 212 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
rs7914 CBL — 0.69 190 vs 376 — Japanese 95+ — — Candidate Region/Gene 23770741
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  • 25 of 1635 variants