Denigma Buck Institute Health Extension

Search
Search by variant, gene, study or associated filed (example: ADRB2)
Search by Gene Ontology term (example: insulin)
polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
Arg 213 ->His SULT1A1 — 0.017 Total 165 — Nigerian, Caucasian range 17- 90 SULT1A1*2 — — 9854023
- HRAS1 — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls 1 (specifically for SIRT3 in a French population) French, German, Italian centenarians; see notes — — - 19367319
- SIRT3 — 0.145 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
- TH — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
- INS — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
- IGF2 — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs4073591 — — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs4073590 DEAF1 — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs11040489 KRTAP5-6 — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs4930001 — — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs800140 TSPAN32 — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs16928120 — — 0.05 see notes; stratified by population; total = 1321 cases versus 1140 controls — French, German, Italian centenarians; see notes — — - 19367319
rs1800629 TNFa — 0.168 See Description for details — Italian Comparison 1: 66-91. Comparison 2: >88 — — Candidate Region/Gene 21865054
rs361525 TNFa — 0.156 See Description for details — Italian Comparison 1: 66-91. Comparison 2: >88 — — Candidate Region/Gene 21865054
192 PON1 1.26 0.007 Italian: 308 vs 579; Northern Irish: 296 vs 296 — Irish Italian: Mean age 100.8 +/- 2.1; Northern Irish: Mean age 89.8 +/- 5.7 Q — Candidate Region/Gene 15050299
rs2542052 APOC3 — 0.0001 Centenarians (n = 213) their offspring (n = 216) vs 258 — Ashkenazi Jewish Mean age 98.2 A — — 16602826
rs5882 CETP — 0.069 Centenarians (n = 213) their offspring (n = 216) vs 258 — Ashkenazi Jewish Mean age 98.2 A — — 16602826
rs2542052 APOC3 — 0.0001 Centenarians (n = 213) their offspring (n = 216) vs 258 — Ashkenazi Jewish mean age 98.2 A — Candidate Region/Gene 16602826
9 mtDNA haplogroups mtDNA haplogroup 0.38 0.025 98 vs. 117 — Chinese 90-100 years old J non-J - 18759861
Haplogroup J — 0.38 0.025 98 vs 117 — Chinese 90–100 — — Candidate Region/Gene 18759861
rs2853826 MT-ND3 — 0.219 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs3928306 MT-RNR2 0.49 0.027 98 vs 117 — Chinese 90–100 A — Candidate Region/Gene 18759861
rs28359172 MT-ND5 0.30 0.003 98 vs 117 — Chinese 90–100 G — Candidate Region/Gene 18759861
rs73598374 ADA 0.32 0.0056 97 vs 261 — Italian >88 G*/G* A*+ Candidate Region/Gene 21865054
5178 adenine/cytosine ND2 — 0.363 95 vs 298 — Chinese 76.2±5.0 C — Candidate Region/Gene 12384792
  • Page 1 of 66
  • 25 of 1635 variants