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| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4537545 | IL6R | — | 3e-18 | 308 | — | American, European, Ashkenazi Jewish | 75.7 | — | — | Candidate Region/Gene | 19249341 |
| DRD4 7R allele | DRD4 | — | 3.5e-08 | 310 vs 2909 | — | European | mean age 95.2 years | — | — | Candidate Region/Gene | 23283341 |
| rs7896005 | SIRT1 | 2.38 | 0.003 | 224 vs 293 | 170 vs 220 | Caucasian, European | 90-103, 98+ (replication) | G | — | Candidate Region/Gene | 21972126 |
| rs132793 | XRCC6 | — | 0.74 | 224 vs 293 | 170 vs 220 | Caucasian, European | 90-103, 98+ (replication) | — | — | Candidate Region/Gene | 21972126 |