| polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
| APOE e2,e3,e4 | APOE | — | 0.05 | 185 vs 486 | — | Finn | Over 100 | E4 | e2 | Candidate Region/Gene | 8018664 |
| many SNPs | TH | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | IGF2 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | INS | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| many SNPs | HRAS1 | — | 0.05 | 1321 vs 1140 | — | Italian | Mean age 101.9 (southern Italian), 101.0 (northern-central Italian), 104.41 (German), 103.1 (French) | — | — | Candidate Region/Gene | 19367319 |
| indel | ACE1 | — | 0.05 | 82 vs 252 | — | Italian | Mean age 100 +/- 2 | — | — | Candidate Region/Gene | 12954489 |
| Not specified | IL2 | — | 0.05 | 470 vs 120 | — | Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| Not specified | IFNG | — | 0.05 | 707 vs 339 | — | Turkish, Polish, Italian, Bulgarian | Age range: 65-99 | — | — | Candidate Region/Gene | 21299522 |
| Arg156Arg | ERCC2 | — | 0.05 | 149 vs 413 | — | Polish | Mean age 101.1 | — | — | Candidate Region/Gene | 19707883 |
| Asp312Asn | ERCC2 | — | 0.05 | 149 vs 413 | — | Polish | Mean age 101.1 | — | — | Candidate Region/Gene | 19707883 |
| rs147610191 | APOA4 | — | 0.05 | 229 vs 571 | — | Calabrian | 81–109 (median 101) | — | — | Candidate Region/Gene | 12556235 |
| rs2071069 | TPI1 | — | 0.05 | 1422 vs 967 | — | German | mean age: 98.8, age range: 95–110 | (SNP is G/A) | — | Candidate Region/Gene | 18510744 |
| rs2071065 | TPI1 | — | 0.05 | 1422 vs 967 | — | German | mean age: 98.8, age range: 95–110 | (SNP is T/C) | — | Candidate Region/Gene | 18510744 |
| rs2764264 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | T | — | Candidate Region/Gene | 20849522 |
| rs7762395 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | G | — | Candidate Region/Gene | 20849522 |
| rs13217795 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | T | — | Candidate Region/Gene | 20849522 |
| rs9400239 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | C | — | Candidate Region/Gene | 20849522 |
| rs9398172 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | A | — | Candidate Region/Gene | 20849522 |
| rs479744 | FOXO3 | — | 0.05 | 1089 vs 736 | — | Danish | 92–93 | (can't figure out using ensemble and NCBI) | — | Candidate Region/Gene | 20849522 |
| APOC3-SstI-RFLP (3'UTR, 3238 nt) | APOC3 | — | 0.05 | 229 vs 571 | — | Calabrian | 81–109 (median 101) | — | — | Candidate Region/Gene | 12556235 |
| rs1801274 | FCGR2A | — | 0.05 | 408 vs 446 vs 454 | — | German | 100–110/ mean101.3 | (SNP is His/Arg) | — | Candidate Region/Gene | 16893392 |
| HP1/2 common polymorphism | HP | — | 0.05 | 200 (cases) vs 539 (initial) (initial) | — | Italian | >88 | — | — | Candidate Region/Gene | 21703254 |
| -351A/G | ESR1 | — | 0.05 | 148 vs 414 | — | Polish | 99.6-107.2; mean= 101.1±1.2 | — | — | Candidate Region/Gene | 20599431 |
| mt5178A | ND2 | — | 0.05 | 95 vs 105 | — | Chinese | Mean age 76 | — | АА | Candidate Region/Gene | 12384792 |
| rs11279109 - SI000565Q | APOB | — | 0.05 | 191 (case) vs 53 | — | Chinese | > 90 baseline, Mean age 97 +/- 3 | D - S | D - M | Candidate Region/Gene | 17393087 |
