Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs4537545 IL6R — 3e-18 308 — American, European, Ashkenazi Jewish 75.7 — — Candidate Region/Gene 19249341
rs1528753 — — 8.1e-08 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs3129046 — 0.66 2.21e-07 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs1610742 — 0.66 3.02e-07 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
HRAS1 LASS1 (CGT) APOE — 6.91e-07 204 vs 251 — American — — — Candidate Region/Gene 20569235
HRAS1 LASS1 (CGT) APOE — 1e-06 79 vs 88 — American — — — Candidate Region/Gene 20569235
rs10493513 — — 1.5e-06 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs1610601 — 0.68 1.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs2338013 — 0.67 2.07e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs4574762 — 0.19 2.29e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs2371208 — — 2.6e-06 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs10493514 — — 2.8e-06 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
rs6504441 PRKCA 0.60 2.87e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs12413082 MSRB2 0.53 3.33e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs1633063 — 0.68 3.82e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs3129063 — 0.67 4.33e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs513154 IMPG2 0.52 4.65e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs1582594 — 1.87 4.76e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
rs158869 — 1.37 4.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs350450 — 0.69 6.34e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs10923806 — 2.30 7.24e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
HRAS1 LASS1 (CGT) APOE — 9e-06 19 vs 73 — Georgian — — — Candidate Region/Gene 20569235
rs29228 — 0.68 9.12e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
rs1575892 — 0.45 9.32e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
HRAS1 LASS1 (CCT) APOE — 1e-05 128 vs 115 — Georgian — — — Candidate Region/Gene 20569235
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  • 25 of 543 variants