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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
rs4420638 APOE 9.6e-08 4445 total (each a part of sibship of 2-5 siblings) Caucasian, European 90 Genome-Wide Association Study 23286790
rs7896005 SIRT1 2.38 0.003 224 vs 293 170 vs 220 Caucasian, European 90-103, 98+ (replication) G Candidate Region/Gene 21972126
rs132793 XRCC6 0.74 224 vs 293 170 vs 220 Caucasian, European 90-103, 98+ (replication) Candidate Region/Gene 21972126
  • 3 variants