polymorphism | factor | odds ratio | pvalue | initial number | replication number | Population | age of cases | shorter lived allele | longer lived allele | study type | reference |
rs3129046 | — | 0.66 | 2.21e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610742 | — | 0.66 | 3.02e-07 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1610601 | — | 0.68 | 1.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs2338013 | — | 0.67 | 2.07e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1633063 | — | 0.68 | 3.82e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs3129063 | — | 0.67 | 4.33e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs158869 | — | 1.37 | 4.98e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs350450 | — | 0.69 | 6.34e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs29228 | — | 0.68 | 9.12e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs1575892 | — | 0.45 | 9.32e-06 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs16947526 | — | 0.56 | 1.23e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs11790055 | — | 1.38 | 1.49e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs10959258 | — | 1.36 | 1.86e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
rs9595687 | — | 0.49 | 2.09e-05 | 763 vs 1085 | 754 vs 850 | German | Mean age 99.7 | — | — | Genome-Wide Association Study | 21740922 |
- | HRAS1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | 1 (specifically for SIRT3 in a French population) | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | TH | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | INS | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
- | IGF2 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073591 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4073590 | DEAF1 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs11040489 | KRTAP5-6 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs4930001 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs800140 | TSPAN32 | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs16928120 | — | — | 0.05 | see notes; stratified by population; total = 1321 cases versus 1140 controls | — | French, German, Italian | centenarians; see notes | — | — | - | 19367319 |
rs2071069 | TPI1 | — | 0.05 | 1422 vs 967 | — | German | mean age: 98.8, age range: 95–110 | (SNP is G/A) | — | Candidate Region/Gene | 18510744 |