Continuous Longevity Meeting | 3 | 4 | Debonneuil; Wuttke; Singh; Maidano | The **Worldwide Continuous Longevity Meeting** is a continuous ``discussion channel`` where anyone can decide to launch global collaborative presentations. The inventor **Edouard Debonneuil** proposed to incorporate it as an organ of the ``Internatio... |
Materials in Different Languages | 1 | 2 | Turchin; Coernette | Content on promoting longevity written/spoken/rendered in one language should be translated and promoted into other languages. A priority is to have at least ``English versions`` of everything. Optionally possibilities to translate into other local ... |
Denigma | 5 | 9 | Fuellen; Magalhaes; Debonneuil; Kulaga; Wuttke; Adams; Borisoglebsky; Fortney; Hall | Denigma is the digital Enigma destined to decipher biological phenomena. All information of an organism is encoded in its genome and can be decrypted via the combined effort of humans and machines. For this, Denigma was build for.
Specifically, Deni... |
Collaborative Knowledge-Management | 1 | 2 | Kulaga; Wuttke | We will establish **new kind of collaboration models** between people (including Researches) and in **Graph representation of knowledge**.
``Collaboration and knowledge-management websystems`` are the clue that **increases collective intelligence*... |
Logo Contest | 1 | 3 | Silvennoinen; Flatt; Maidano | The individual **longevity parties** operate under the ``banner`` of the International Longevity Alliance (**ILA**). However, the ILA does not yet have such an unifying banner.
The logo will be utilized **cross-nationally** with only minor modific... |
in situ Regeneration | 1 | 2 | Wuttke; Zamani |
:Abstract: As we are young everything regenerates perfectly. In fact, our body harbors the plan to reconstruct itself from scratch which is localized in the nucleus of each of our body cells. However, as we grow up our regenerative capacities decre... |
Circadian Rhythm | 2 | 4 | Kapahi; Magalhaes; Wuttke; Katewa | Most animals have rest/activity/rhythms that are powered by an endogenous timing mechanism, the circadian system. With aging the rhythm becomes weaker [23223368].
Middle aged flies exhibit reduced activity level in comparison with young controls. ... |
Denigma | 5 | 9 | Fuellen; Magalhaes; Debonneuil; Kulaga; Wuttke; Adams; Borisoglebsky; Fortney; Hall | Denigma is the digital Enigma destined to decipher biological phenomena. All information of an organism is encoded in its genome and can be decrypted via the combined effort of humans and machines. For this, Denigma was build for.
Specifically, Deni... |
Pentose Phosphate Pathway | 2 | 3 | Magalhaes; Wuttke; Tang | The pentose phosphate pathway chiefly generates reduction equivalents in the form of NADPH:
3 G6P + 6 NADPH+ + 3 H2O = 6 NADPH + 6 H+ + 3 CO2 + 2 F6P + GAP
6 equivalents of NADPH is quite a lot for just three sugars. NADPH might scavenge ROS.
... |
Tissue-Specific DR-Effects | 2 | 4 | Kapahi; Magalhaes; Wuttke; Li |
:Abstract: A restricted diet without malnutrition highly effectively counteracts ageing in several species and extends robustly their lifespan. How lifespan is extended remains enigmatic. We utilized tissue-specific gene expression data in *Droso... |
Gerontology | 2 | 0 | | The ``Gerontology Ontology`` (the Ontology for Aging and Longevity, ``GERO``) is a mid-level ontology representing aging-related phenomena from the molecular and cellular levels to the social and demographic level. It aims to support gerontological ... |
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