Polymorphism: rs4646994
rs4646994
(
SNPedia |
23andMe
)
Variant Type: STR
Location: 17q23.3
Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640
Factors:
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
(
1636
/
ENSG00000159640
)
Description:
"No association of the ACE gene insertion/deletion polymorphism with longevity was observed in our Han Chinese population" Detailed P-value data: No significant differences were observed between the two groups in the distribution of Genotypes (Overall: 0.849, Adjust for gender: Male, 0.994; Female, 0.797) and Alleles (Overall: 0.849, Adjust for gender: Male, 0.969; Female, 0.884)
Trivial name is ACE Alu insertion/deletion.
Ethnicity:
Chinese
Age of cases: >90 years
Finding: Negative
Statistics
- Number of cases/controls: 399 vs 302 (initial)
- p-value:
0.849
[0.849]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
19502260: Lack of genetic association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and longevity in a Han Chinese population.
Choice: Clean
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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