Polymorphism: rs1800591-rs61733139
rs1800591-rs61733139
(
SNPedia |
23andMe
)
Variant Type: Haplotype
Location: 4q24
Factor:
- Symbol: MTTP
- Name: microsomal triglyceride transfer protein
- Entrez ID: 4547
- Ensembl ID: ENSG00000138823
Factors:
MTTP
microsomal triglyceride transfer protein
(
4547
/
ENSG00000138823
)
Description:
The two MTP polymorphisms are in complete LD. "We found no association of an MTP haplotype with longevity in either of our Leiden studies." Meta-analysis led to same conclusion.
T-Q haplotype was studied. Initial number refers to octogenarians vs controls
Ethnicity:
Dutch
Age of cases: Mean age 87.5±3.1
Finding: Negative
Statistics
- Number of cases/controls: 655 vs 244 (initial)
- p-value:
0.46
[0.46]
- Significant: No
Study Design
- Classifications:
No Age Effect
- Study type: Meta-Analysis
- Technology: PCR based probes
Reference:
16611701: Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies.
Choice: Curate
Created: July 1, 2013, 1:04 p.m.
Updated: Aug. 9, 2014, 11:31 p.m.
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