Polymorphism: rs2075650
rs2075650
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Description:
P value reported is uncorrected, but association did remain significant after correcting for multiple testing. P value for association with age at death.
Ethnicity:
American,
British
Age of cases: Age range 50-108; mean age at death 80.2
Shorter lived allele: C
Longer lived allele: T
Finding: Positive
Statistics
- Number of cases/controls: 1364 (initial)
- p-value:
0.000527
[0.000527]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: Illumina 300, Illumina 610
Reference:
22445811: Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).
Choice: Clean
Created: Aug. 14, 2013, 12:50 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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