Polymorphism: rs132793
rs132793
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 22q13.2
Factor:
- Symbol: XRCC6
- Name: X-ray repair complementing defective repair in Chinese hamster cells 6
- Entrez ID: 2547
- Ensembl ID: ENSG00000196419
Factors:
XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
(
2547
/
ENSG00000196419
)
Description:
XRCC6 variant was not associated with longevity, though it had a significant effect on telomere length.
Ethnicity:
Caucasian,
European
Age of cases: 90-103, 98+ (replication)
Finding: Negative
Statistics
- Number of cases/controls: 224 vs 293 (initial)
| 170 vs 220 (replication)
- p-value:
0.74
[ N/A]
- Significant: No
Study Design
- Study type: Candidate Region/Gene
- Technology: Illumina GoldenGate
Reference:
21972126: Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 8, 2014, 1:17 p.m.
Edit
(
Admin) |
Delete