Polymorphism: rs207444
rs207444
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 2p23.1
Factor:
- Symbol: XDH
- Name: xanthine dehydrogenase
- Entrez ID: 7498
- Ensembl ID: ENSG00000158125
Factors:
XDH
xanthine dehydrogenase
(
7498
/
ENSG00000158125
)
Description:
No OR mentioned, only β-coefficient = 4.043
Ethnicity:
Danish
Age of cases: 92.2–93.8 (mean age 93.2) w/ 11.4 years follow-up
Shorter lived allele: G - Unsure
Finding: Positive
Statistics
- Number of cases/controls: 1089 (see notes - follow-up study) (initial)
| 563 (see notes - follow-up study) (replication)
- p-value:
0.046
[0.046]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
Reference:
22406557: Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
Choice: Curate
Created: July 2, 2013, 2:48 a.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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