Polymorphism: rs4646994
rs4646994
(
SNPedia |
23andMe
)
Variant Type: Deletion
Location: 17q23.3
Factor:
- Symbol: ACE
- Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
- Entrez ID: 1636
- Ensembl ID: ENSG00000159640
Factors:
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
(
1636
/
ENSG00000159640
)
Description:
Total population consists of Caucasian Gaucho population and Japanese population, both living in the South of Brasilia.
Results are only significant in Gaucho population (GP), not Japanese population (JP)
Ethnicity:
Brazilian
Age of cases: 10-104
Shorter lived allele: I
Longer lived allele: D (only for Gaucho population)
Finding: Positive
Statistics
- Number of cases/controls: 834 (initial)
- Odds ratio: 2.25
- Odds ratio type: Longer
- p-value:
0.003
[0.003 (only in Gaucho population)]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Candidate Region/Gene
- Technology: PCR
Reference:
14528043: Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazil's southern region: association with age.
Choice: Clean
Created: July 1, 2013, 10:43 a.m.
Updated: Aug. 8, 2014, 1:05 p.m.
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