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Longevity DB
Genetic variants implicated in human longevity.
Polymorphism:
rs6701445
rs6701445
(
SNPedia
|
23andMe
)
Variant Type:
SNP
Location:
1q42.13
Factor:
- Symbol:
TAF5L
- Name:
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
- Entrez ID:
27097
- Ensembl ID:
ENSG00000135801
Factors:
TAF5L
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
(
27097
/
ENSG00000135801
)
Ethnicity:
Italian
Age of cases:
90–109
Finding:
Positive
Statistics
- Number of cases/controls:
410 vs 553 (initial)
- Odds ratio:
1.84
- Odds ratio type:
- p-value:
4.19e-05 [0.0000419]
- Significant:
Nominally
Study Design
- Classifications:
No Age Effect
- Study type:
Genome-Wide Association Study
- Technology:
Illumina HumanHap BeadChip 317K duo system
Reference:
21612516: Association study on long-living individuals from Southern Italy identifies rs10491334 in the CAMKIV gene that regulates survival proteins.
Choice:
Clean
Created:
Aug. 20, 2013, 9:23 p.m.
Updated:
Aug. 8, 2014, 1:05 p.m.
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